Cancer and Thrombosis: New Treatments, New Challenges
The direct-acting oral anticoagulant (DOAC) has become an alternative to low-molecular-weight heparin (LMWH) for treatment and prophylaxis of venous thromboembolism (VTE) in cancer patients. The clinicians are, however, faced with difficult decisions regarding DOAC treatment: Which patients cannot u...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Medical Sciences |
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| Online Access: | https://www.mdpi.com/2076-3271/9/2/41 |
| _version_ | 1797531504833724416 |
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| author | Anders Erik Astrup Dahm |
| author_facet | Anders Erik Astrup Dahm |
| author_sort | Anders Erik Astrup Dahm |
| collection | DOAJ |
| description | The direct-acting oral anticoagulant (DOAC) has become an alternative to low-molecular-weight heparin (LMWH) for treatment and prophylaxis of venous thromboembolism (VTE) in cancer patients. The clinicians are, however, faced with difficult decisions regarding DOAC treatment: Which patients cannot use DOACs? Should incidental VTE be treated similar to symptomatic VTE? Is it safe to give DOACs to patients with gastrointestinal or urogenital cancers? How about drug–drug interactions? Should all cancer patients receive thromboprophylaxis? Is arterial thrombosis a problem? The current article reviews the available literature regarding these questions and aims to provide practical solutions based on data from the clinical trials and new guidelines. |
| first_indexed | 2024-03-10T10:44:45Z |
| format | Article |
| id | doaj.art-4a2ff03e149f4a1aae907cc9f7a3bb49 |
| institution | Directory Open Access Journal |
| issn | 2076-3271 |
| language | English |
| last_indexed | 2024-03-10T10:44:45Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medical Sciences |
| spelling | doaj.art-4a2ff03e149f4a1aae907cc9f7a3bb492023-11-21T22:38:37ZengMDPI AGMedical Sciences2076-32712021-06-01924110.3390/medsci9020041Cancer and Thrombosis: New Treatments, New ChallengesAnders Erik Astrup Dahm0Department of Hematology, Akershus University Hospital, 1478 Lørenskog, NorwayThe direct-acting oral anticoagulant (DOAC) has become an alternative to low-molecular-weight heparin (LMWH) for treatment and prophylaxis of venous thromboembolism (VTE) in cancer patients. The clinicians are, however, faced with difficult decisions regarding DOAC treatment: Which patients cannot use DOACs? Should incidental VTE be treated similar to symptomatic VTE? Is it safe to give DOACs to patients with gastrointestinal or urogenital cancers? How about drug–drug interactions? Should all cancer patients receive thromboprophylaxis? Is arterial thrombosis a problem? The current article reviews the available literature regarding these questions and aims to provide practical solutions based on data from the clinical trials and new guidelines.https://www.mdpi.com/2076-3271/9/2/41cancerthrombosistreatmentprophylaxisanticoagulation |
| spellingShingle | Anders Erik Astrup Dahm Cancer and Thrombosis: New Treatments, New Challenges Medical Sciences cancer thrombosis treatment prophylaxis anticoagulation |
| title | Cancer and Thrombosis: New Treatments, New Challenges |
| title_full | Cancer and Thrombosis: New Treatments, New Challenges |
| title_fullStr | Cancer and Thrombosis: New Treatments, New Challenges |
| title_full_unstemmed | Cancer and Thrombosis: New Treatments, New Challenges |
| title_short | Cancer and Thrombosis: New Treatments, New Challenges |
| title_sort | cancer and thrombosis new treatments new challenges |
| topic | cancer thrombosis treatment prophylaxis anticoagulation |
| url | https://www.mdpi.com/2076-3271/9/2/41 |
| work_keys_str_mv | AT anderserikastrupdahm cancerandthrombosisnewtreatmentsnewchallenges |