Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports
<p class="Standard"><span lang="EN-US">Background. Angioedema is a rare but potentially very serious complication of treatment with angiotensin converting enzyme inhibitors (ACEI). Angioedema is due to the accumulation of bradykinin, because angiotensin<s> </...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Slovenian Medical Association
2016-01-01
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| Series: | Zdravniški Vestnik |
| Subjects: | |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/1349 |
| _version_ | 1831813758237802496 |
|---|---|
| author | Erik Rupnik Stojan Kariž Črtomir Iglič Mihaela Zidarn |
| author_facet | Erik Rupnik Stojan Kariž Črtomir Iglič Mihaela Zidarn |
| author_sort | Erik Rupnik |
| collection | DOAJ |
| description | <p class="Standard"><span lang="EN-US">Background. Angioedema is a rare but potentially very serious complication of treatment with angiotensin converting enzyme inhibitors (ACEI). Angioedema is due to the accumulation of bradykinin, because angiotensin<s> </s>converting enzyme is the key enzyme for its degradation.</span></p><p class="Standard"><span lang="EN-US">Case reports. We present two patients with life-threatening angioedema while taking ACEI. Both patients had already had episodes of angioedema. Angioedema didn't respond to adrenaline. In both patients intubation was difficult.</span></p><p class="Standard"><span lang="EN-US">Conclusion. In the acute phase of angioedema due to ACEI it is necessary to protect the airways. Bradykinin receptor inhibitors shorten the duration of episodes of angioedema. In the long term it is essential to permanently avoid ACEI.</span></p> |
| first_indexed | 2024-12-22T22:01:07Z |
| format | Article |
| id | doaj.art-4a32ff2593574d9095b0e413dbef4032 |
| institution | Directory Open Access Journal |
| issn | 1318-0347 1581-0224 |
| language | English |
| last_indexed | 2024-12-22T22:01:07Z |
| publishDate | 2016-01-01 |
| publisher | Slovenian Medical Association |
| record_format | Article |
| series | Zdravniški Vestnik |
| spelling | doaj.art-4a32ff2593574d9095b0e413dbef40322022-12-21T18:11:07ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242016-01-0184121066Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reportsErik Rupnik0Stojan Kariž1Črtomir Iglič2Mihaela Zidarn3General Hospital IzolaGeneral Hospital IzolaGeneral Hospital IzolaUniversity Clinic of Respiratory and Allergic Diseases<p class="Standard"><span lang="EN-US">Background. Angioedema is a rare but potentially very serious complication of treatment with angiotensin converting enzyme inhibitors (ACEI). Angioedema is due to the accumulation of bradykinin, because angiotensin<s> </s>converting enzyme is the key enzyme for its degradation.</span></p><p class="Standard"><span lang="EN-US">Case reports. We present two patients with life-threatening angioedema while taking ACEI. Both patients had already had episodes of angioedema. Angioedema didn't respond to adrenaline. In both patients intubation was difficult.</span></p><p class="Standard"><span lang="EN-US">Conclusion. In the acute phase of angioedema due to ACEI it is necessary to protect the airways. Bradykinin receptor inhibitors shorten the duration of episodes of angioedema. In the long term it is essential to permanently avoid ACEI.</span></p>http://vestnik.szd.si/index.php/ZdravVest/article/view/1349isolated angioedema, angiotensin converting enzyme inhibitors, bradykinin, icatibant, difficult intubation |
| spellingShingle | Erik Rupnik Stojan Kariž Črtomir Iglič Mihaela Zidarn Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports Zdravniški Vestnik isolated angioedema, angiotensin converting enzyme inhibitors, bradykinin, icatibant, difficult intubation |
| title | Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports |
| title_full | Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports |
| title_fullStr | Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports |
| title_full_unstemmed | Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports |
| title_short | Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports |
| title_sort | life threatening angioedema induced by angiotensin converting enzyme inhibitor two case reports |
| topic | isolated angioedema, angiotensin converting enzyme inhibitors, bradykinin, icatibant, difficult intubation |
| url | http://vestnik.szd.si/index.php/ZdravVest/article/view/1349 |
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