Nobiletin acts as a potential anticancer agent against osteosarcoma by regulating ERK and AKT signaling pathways

Nobiletin acts as a potential anticancer agent against osteosarcoma by regulating ERK and AKT signaling pathways

The current study was aimed to evaluate the anti-proliferative activity of nobiletin, a flavonoid, on osteosarcoma cell line, SaOS-2. Furthermore, we attempted to investigate the signaling pathways involved in the cell growth inhibition mechanism. Upon exposure, nobiletin showed significant cell inh...

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Bibliographic Details
Main Authors: Fu-Wen Niu, Yong-Jie Zhang, Kun Li, Mao-Shu Zhang
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2014-09-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Antiproliferative
Nobiletin
Osteosarcoma
Signaling pathway
Online Access:https://www.banglajol.info/index.php/BJP/article/view/19567

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