P-114 APPLICATION OF THE DONOR RISK INDEX IN LIVER TRANSPLANTATION IN THE MAIN TRANSPLANT CENTER IN PERU

Introduction and Objectives: The evaluation of cadaveric donors through the application of the donor-recipient risk index (DRI) since 2006 in the USA has been useful in the standardization of criteria during organ allocation in liver transplantation. This study aimed to apply the DRI > or < 1....

Full description

Bibliographic Details
Main Authors: P.Martin Padilla-Machaca, Omar Mantilla, José Rivera, Alfonso Solar, Bertha Cárdenas, Carmen Cerrón, Saul Espinoza, Wilmer Bacilio, A Montufar, Carlos Rondón
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268123001023
Description
Summary:Introduction and Objectives: The evaluation of cadaveric donors through the application of the donor-recipient risk index (DRI) since 2006 in the USA has been useful in the standardization of criteria during organ allocation in liver transplantation. This study aimed to apply the DRI > or < 1.7 and the relationship with morbidity and mortality, hospital stay, post-reperfusion syndrome, diagnosis, and origin, steatosis, BMI, cold ischemia times (WIT), Child-Pugh score and MELD score in our center. Materials and Methods: Descriptive, cross-sectional, retrospective study. The medical records of all liver transplant patients were reviewed to extract demographic data and clinical characteristics based on the criteria established in the DRI assessment. Results: 78 patients out of 303 met the criteria for evaluation registration, DRI < 1.7: 70.51% (mortality 16.36%), DRI > 1.7: 29.8% (mortality: 30.43). Post reperfusion syndrome: 47.82%. Cause of brain death: Traumatic brain injury: 43.58%, stroke: 41.02%, anoxic brain injury: 11.53%. Male: 60.25% and female: 39.74%. Donor graft weight: IDR <1.7: 1412 gr (700-2440g), WIT: 5.91 h (1.38-11.4 h), Age: 31 y (10-55), BMI: 24.93 (12.11-33.33), brain death time: 24 h and admission time: 4.3 hours, in the group with DRI > 1.7 graft weight: 1407 g (336-1900), WIT: 7.4 h (4-12.24), age: 51.22 y (29-67), BMI: 26.27 (26.23-29.38), brain death time: 24.5 h and admission time: 3 h. DRI group < 1.7: mild steatosis: 80%, moderate: 18% and in the IDR group > 1.7: mild steatosis: 87% and moderate in 13%. (see table 1) Conclusions: Medical-surgical morbidity and mortality, post-reperfusion syndrome, hospital stay, stroke, BMI, and use of SPLIT grafts were higher in patients with IDR > 1.7. Other variables studied had no statistical relationship. We conclude that the IDR should be included in the evaluation of donors in our reality.
ISSN:1665-2681