Increased Serpina3n release into circulation during glucocorticoid‐mediated muscle atrophy

Increased Serpina3n release into circulation during glucocorticoid‐mediated muscle atrophy

Abstract Background Glucocorticoids (GC) play a major role in muscle atrophy. As skeletal muscle is a secretory organ, characterization of the muscle secretome elicited by muscle atrophy should allow to better understand the cellular mechanisms and to identify circulating biomarkers of this conditio...

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Bibliographic Details
Main Authors: Marine Gueugneau, Donatienne d'Hose, Caroline Barbé, Marie deBarsy, Pascale Lause, Dominique Maiter, Laure B. Bindels, Nathalie M. Delzenne, Laurent Schaeffer, Yann‐Gaël Gangloff, Christophe Chambon, Cécile Coudy‐Gandilhon, Daniel Béchet, Jean‐Paul Thissen
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Serpina3n
Glucocorticoids
Muscle atrophy
Biomarker
Online Access:https://doi.org/10.1002/jcsm.12315

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