Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives

Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives

In this article, we showed the synthesis of new polycyclic aromatic compounds, such as thienotriazolopyrimidinones, <i>N</i>-(thienotriazolopyrimidine) acetamide, 2-mercapto-thienotriazolo-pyrimidinones, 2-(((thieno-triazolopyrimidine) methyl) thio) thieno-triazolopyrimidines, thieno-pyr...

Full description

Bibliographic Details
Main Authors:	Ameen Ali Abu-Hashem, Sami A. Al-Hussain, Magdi E. A. Zaki
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Molecules
Subjects:	thienopyrimidinone thienotriazolopyrimidinone 1,2,4-triazole thiazine pyrrole oxathiinoquinoxaline
Online Access:	https://www.mdpi.com/1420-3049/26/7/2031

Similar Items

Synthesis A New Bis Oxazine and Thiazine Derivatives and Study Their Biological Activities
by: Dina Saleem M. Ameen
Published: (2023-01-01)

Crystal structure and Hirshfeld surface analysis of a pyrrolo-thiazine complex
by: R. Sribala, et al.
Published: (2021-08-01)

A rapid and effective catalytic pathway for the synthesis of thiazine derivatives employing Zno nanoparticles
by: Raksha Parag Dhankar, et al.
Published: (2024-01-01)

Dithieno[1,4]thiazines and Bis[1]benzothieno[1,4]thiazines—Organometallic Synthesis and Functionalization of Electron Density Enriched Congeners of Phenothiazine
by: Lars May, et al.
Published: (2020-05-01)

Synthesis and characterization of new Oxazine , Thiazine and Pyrazol derived from chalcones
by: Baghdad Science Journal
Published: (2014-06-01)

In Vitro and In Vivo Anti-Breast Cancer Activities of Some Newly Synthesized 5-(thiophen-2-yl)thieno-[2,3-d]pyrimidin-4-one Candidates
by: Abd El-Galil E. Amr, et al.
Published: (2019-06-01)

First Metal-Free Synthesis of Tetracyclic Pyrido and Pyrazino Thienopyrimidinone Molecules
by: Mohammed Aounzou, et al.
Published: (2018-05-01)

Bioactive Thiazine and Benzothiazine Derivatives: Green Synthesis Methods and Their Medicinal Importance
by: Syed Lal Badshah, et al.
Published: (2016-08-01)

3-Benzoyl-2-hydroxy-3a-[(3-methylquinoxalin-2-yl)methyl]-1<i>H</i>-pyrrolo[2,1-<i>c</i>][1,4]benzothiazine-1,4(3a<i>H</i>)-dione
by: Ekaterina A. Lystsova, et al.
Published: (2023-12-01)

Carbene-Catalyzed Atroposelective Annulation for Quick Access to Axially Chiral Thiazine Derivatives
by: Xiaoqun Yang, et al.
Published: (2023-05-01)

Tetrahydro-1,4-thiazine-3,5-dione
by: R. Alan Aitken, et al.
Published: (2018-12-01)

Synthesis of 6-Membered-Ring Fused Thiazine-Dicarboxylates and Thiazole-Pyrimidines via One-Pot Three-Component Reactions
by: Reagan L. Mohlala, et al.
Published: (2021-09-01)

Stereoselective Synthesis and Cytoselective Toxicity of Monoterpene-Fused 2-Imino-1,3-thiazines
by: Zsolt Szakonyi, et al.
Published: (2014-10-01)

1,3-Thiazine, 1,2,3,4-Dithiadiazole, and Thiohydrazide Derivatives Affect Lipid Bilayer Properties and Ion-Permeable Pores Induced by Antifungals
by: Anastasiia A. Zakharova, et al.
Published: (2020-06-01)

Antiproliferative Activity of (−)‐Isopulegol‐based 1,3‐Oxazine, 1,3‐Thiazine and 2,4‐Diaminopyrimidine Derivatives
by: Fatima Z. Bamou, et al.
Published: (2022-10-01)

Synthesis, Characterization and Antiproliferative Evaluation of Pt(II) and Pd(II) Complexes with a Thiazine-Pyridine Derivative Ligand
by: Silvia Gutiérrez-Tarriño, et al.
Published: (2021-04-01)

Synthesis of Some Thienopyrimidine Derivatives
by: Hassan M. Al-Hazimi, et al.
Published: (2006-07-01)

Synthesis, anticancer activity and molecular docking of new quinolines, quinazolines and 1,2,4-triazoles with pyrido[2,3-d] pyrimidines
by: Ameen Ali Abu-Hashem, et al.
Published: (2024-03-01)

Synthesis and Characterization of Some New Thiazine , Azetidine and Thiazolidine Compounds Containing 1,3,4Thiadiazole Moiety And Their Antibacterial Study
by: Ali H. Samir, et al.
Published: (2017-04-01)

Crystal structure of the 1:1 adduct of 2,3-diphenyl-3,4,5,6-tetrahydro-2H-1,3-thiazin-4-one with triphenyltin chloride
by: Hemant P. Yennawar, et al.
Published: (2016-03-01)

Synthesis of Substituted Pyrrole Derivatives Based on 8-Azaspiro[5.6]dodec-10-ene Scaffold
by: Ildar R. Iusupov, et al.
Published: (2024-01-01)

3,4-Dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol
by: Latifa El Ouasif, et al.
Published: (2017-03-01)

Triazole-Modified Peptidomimetics: An Opportunity for Drug Discovery and Development
by: Agnieszka Staśkiewicz, et al.
Published: (2021-05-01)

Iron(III) promoted oxidative annulation of benzylic C-H bonds in (<i>α</i>-amino)arylacetic acids for synthesis of 4-aryl pyrrolo[1,2-<i>a</i>]quinoxalines
by: Tuan Hoang Ho, et al.
Published: (2023-12-01)

Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
by: Graziella Tocco, et al.
Published: (2023-09-01)

New axially chiral molecular scaffolds with antibacterial activities against Xanthomonas oryzae pv. oryzae for protection of rice
by: Chen, Yanlin, et al.
Published: (2022)

Preparation and Characterization of New Heterocyclic Derivatives, Six and Five Ring from Acetanilide
by: Zainab Amer Sallal
Published: (2020-12-01)

Sulfur Derivatives of 1,2,4-Triazole: Recently Developed Compounds, Structure Activity Relationship, and Biological Activity: Review article
by: Azhar Mahdi Jasim, et al.
Published: (2024-12-01)

Copper-catalyzed 2,3-dihydro-1,2,4-triazoles synthesis through [3+2]-cycloaddition of nitrile ylides with azodicarboxylates
by: Bao-Gui Cai, et al.
Published: (2024-08-01)

An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine
by: Gildardo Rivera, et al.
Published: (2008-01-01)

Synthesis and Characterization of Some New Morpholine Derivatives
by: Baghdad Science Journal
Published: (2016-06-01)

Multicomponent Synthesis of 3,6-Dihydro-2H-1,3-thiazine-2-thiones
by: Frans J. J. de Kanter, et al.
Published: (2012-02-01)

N-Acetonitrile functionalized 3-nitrotriazole: Precursor to nitrogen rich stable and insensitive energetic materials
by: Prachi Bhatia, et al.
Published: (2024-03-01)

New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity
by: Mohamed T-E Maghraby, et al.
Published: (2023-10-01)

Crystal structures of the sulfones of 2,3-diphenyl-2,3-dihydro-4H-1,3-benzothiazin-4-one and 2,3-diphenyl-2,3-dihydro-4H-pyrido[3,2-e][1,3]thiazin-4-one
by: Hemant P. Yennawar, et al.
Published: (2023-03-01)

4-[(3-Phenyl-4,5-dihydroisoxazol-5-yl)methyl]-2H-benzo[b][1,4]thiazin-3(4H)-one
by: Nada Kheira Sebbar, et al.
Published: (2016-06-01)

Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents
by: Aouad Mohamed Reda, et al.
Published: (2015-06-01)

Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation
by: Rezki Nadjet, et al.
Published: (2017-09-01)

Triazolopyridine, a leitmotif of synthetic methods and pharmacological attributes: An extensive review
by: Popat Mohite, et al.
Published: (2023-10-01)

Synthesis methods of 1,2,3-/1,2,4-triazoles: A review
by: Jinlian Dai, et al.
Published: (2022-09-01)