Sanguinarine Regulates Tumor-Associated Macrophages to Prevent Lung Cancer Angiogenesis Through the WNT/β-Catenin Pathway

Sanguinarine Regulates Tumor-Associated Macrophages to Prevent Lung Cancer Angiogenesis Through the WNT/β-Catenin Pathway

Tumor-associated macrophage (TAM)-mediated angiogenesis in the tumor microenvironment is a prerequisite for lung cancer growth and metastasis. Therefore, targeting TAMs, which block angiogenesis, is expected to be a breakthrough in controlling the growth and metastasis of lung cancer. In this study,...

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Bibliographic Details
Main Authors: Yajing Cui, Yingbin Luo, Qiaohong Qian, Jianhui Tian, Zhihong Fang, Xi Wang, Yaoying Zeng, Jianchun Wu, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
lung cancer
angiogenesis
tumor associated macrophages
sanguinarine
Wnt/β- catenin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.732860/full

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