Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire
Environmental changes related to agricultural practices and activities can impact malaria transmission. In the objective to evaluate this impact on the human-vector contact, the level of human exposure to Anopheles vector bites was assess by an immuno-epidemiological indicator based on the assessmen...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-05-01
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| Series: | Parasite Epidemiology and Control |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S240567311830093X |
| _version_ | 1811223909585911808 |
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| author | Cécile Agnimou Malanfoua Sadia-Kacou Céline Mabot Yobo Maurice Akré Adja André Barembaye Sagna Emmanuel Elanga Ndille Anne Poinsignon Yao Tano Benjamin Guibehi Koudou Franck Remoue |
| author_facet | Cécile Agnimou Malanfoua Sadia-Kacou Céline Mabot Yobo Maurice Akré Adja André Barembaye Sagna Emmanuel Elanga Ndille Anne Poinsignon Yao Tano Benjamin Guibehi Koudou Franck Remoue |
| author_sort | Cécile Agnimou Malanfoua Sadia-Kacou |
| collection | DOAJ |
| description | Environmental changes related to agricultural practices and activities can impact malaria transmission. In the objective to evaluate this impact on the human-vector contact, the level of human exposure to Anopheles vector bites was assess by an immuno-epidemiological indicator based on the assessment of the human IgG antibody response to the Anopheles gambiae gSG6-P1 salivary peptide, previously validated as a pertinent biomarker.Two cross-sectional surveys were carried out in the dry and rainy season in three villages with intensive agricultural plantations (N'Zikro with rubber cultivation, Ehania-V5 and Ehania-V1 with palm oil exploitation) and in a control village without plantations (Ayébo). Overall, 775 blood samples were collected in filter papers from children aged 1 to 14 years-old for immunological analysis by ELISA. The IgG levels to the gSG6-P1 salivary peptide significantly differed between studied villages both in the dry and the rainy seasons (P < 0.0001) and were higher in agricultural villages compared to the control area. In particular, the level of specific IgG in Ehania-V5, located in the heart of palm oil plantations, was higher compared to other agricultural villages. Interestingly, the level of specific IgG levels classically increased between the dry and the rainy season in the control village (P < 0.0001) whereas it remained high in the dry season as observed in the rainy season in agricultural villages.The present study indicated that rubber and oil palm plantations could maintain a high level of human exposure to Anopheles bites during both the dry and rainy seasons. These agricultural activities could therefore represent a permanent factor of malaria transmission risk. Keywords: Anopheles, Agricultural activities, Biomarker, Antibody, Saliva, Malaria risk |
| first_indexed | 2024-04-12T08:40:38Z |
| format | Article |
| id | doaj.art-4a43400b930c427885aad3973106da7c |
| institution | Directory Open Access Journal |
| issn | 2405-6731 |
| language | English |
| last_indexed | 2024-04-12T08:40:38Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Parasite Epidemiology and Control |
| spelling | doaj.art-4a43400b930c427885aad3973106da7c2022-12-22T03:39:54ZengElsevierParasite Epidemiology and Control2405-67312019-05-015Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'IvoireCécile Agnimou Malanfoua Sadia-Kacou0Céline Mabot Yobo1Maurice Akré Adja2André Barembaye Sagna3Emmanuel Elanga Ndille4Anne Poinsignon5Yao Tano6Benjamin Guibehi Koudou7Franck Remoue8Institut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; UFR Biosciences, Université Félix Houphouët Boigny, 08 3800, Abidjan 08, Côte d'IvoireInstitut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; UFR Science de la Nature, Université Nangui Abrogoua, Abidjan, Côte d'IvoireInstitut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; UFR Biosciences, Université Félix Houphouët Boigny, 08 3800, Abidjan 08, Côte d'IvoireInstitut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; MIVEGEC (University of Montpellier, CNRS, IRD): Institut de Recherche pour le Développement (IRD), Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, Montpellier, FranceMIVEGEC (University of Montpellier, CNRS, IRD): Institut de Recherche pour le Développement (IRD), Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, Montpellier, FranceInstitut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; MIVEGEC (University of Montpellier, CNRS, IRD): Institut de Recherche pour le Développement (IRD), Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, Montpellier, FranceUFR Biosciences, Université Félix Houphouët Boigny, 08 3800, Abidjan 08, Côte d'Ivoire; UFR Science de la Nature, Université Nangui Abrogoua, Abidjan, Côte d'IvoireUFR Science de la Nature, Université Nangui Abrogoua, Abidjan, Côte d'Ivoire; Filariasis Programme Support Unit from Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Centre Suisse de Recherches Scientifiques (CSRS), Abidjan, Côte d'IvoireInstitut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire; MIVEGEC (University of Montpellier, CNRS, IRD): Institut de Recherche pour le Développement (IRD), Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, Montpellier, France; Corresponding author at: Institut Pierre Richet (IPR), Institut National de Santé Publique (INSP), 01 BP 1500, Bouaké 01, Côte d'Ivoire.Environmental changes related to agricultural practices and activities can impact malaria transmission. In the objective to evaluate this impact on the human-vector contact, the level of human exposure to Anopheles vector bites was assess by an immuno-epidemiological indicator based on the assessment of the human IgG antibody response to the Anopheles gambiae gSG6-P1 salivary peptide, previously validated as a pertinent biomarker.Two cross-sectional surveys were carried out in the dry and rainy season in three villages with intensive agricultural plantations (N'Zikro with rubber cultivation, Ehania-V5 and Ehania-V1 with palm oil exploitation) and in a control village without plantations (Ayébo). Overall, 775 blood samples were collected in filter papers from children aged 1 to 14 years-old for immunological analysis by ELISA. The IgG levels to the gSG6-P1 salivary peptide significantly differed between studied villages both in the dry and the rainy seasons (P < 0.0001) and were higher in agricultural villages compared to the control area. In particular, the level of specific IgG in Ehania-V5, located in the heart of palm oil plantations, was higher compared to other agricultural villages. Interestingly, the level of specific IgG levels classically increased between the dry and the rainy season in the control village (P < 0.0001) whereas it remained high in the dry season as observed in the rainy season in agricultural villages.The present study indicated that rubber and oil palm plantations could maintain a high level of human exposure to Anopheles bites during both the dry and rainy seasons. These agricultural activities could therefore represent a permanent factor of malaria transmission risk. Keywords: Anopheles, Agricultural activities, Biomarker, Antibody, Saliva, Malaria riskhttp://www.sciencedirect.com/science/article/pii/S240567311830093X |
| spellingShingle | Cécile Agnimou Malanfoua Sadia-Kacou Céline Mabot Yobo Maurice Akré Adja André Barembaye Sagna Emmanuel Elanga Ndille Anne Poinsignon Yao Tano Benjamin Guibehi Koudou Franck Remoue Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire Parasite Epidemiology and Control |
| title | Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire |
| title_full | Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire |
| title_fullStr | Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire |
| title_full_unstemmed | Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire |
| title_short | Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to Anopheles bites in children living near rubber and oil palm cultivations in Côte d'Ivoire |
| title_sort | use of anopheles salivary biomarker to assess seasonal variation of human exposure to anopheles bites in children living near rubber and oil palm cultivations in cote d ivoire |
| url | http://www.sciencedirect.com/science/article/pii/S240567311830093X |
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