Proton and Carbon Ion Irradiation Changes the Process of Endochondral Ossification in an Ex Vivo Femur Organotypic Culture Model

Particle therapy (PT) that utilizes protons and carbon ions offers a promising way to reduce the side effects of radiation oncology, especially in pediatric patients. To investigate the influence of PT on growing bone, we exposed an organotypic rat ex vivo femur culture model to PT. After irradiatio...

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Bibliographic Details
Main Authors: Vanessa Etschmaier, Dietmar Glänzer, Nicole Eck, Ute Schäfer, Andreas Leithner, Dietmar Georg, Birgit Lohberger
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/18/2301