A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots
The screening of several Chinese medicinal herbs for nematocidal properties showed that the ethanol extract of Liriope muscari fibrous roots possessed significant nematocidal activity against the pine wood nematode (Bursaphelenchus xylophilus). From the ethanol extract, a new constituent (1,4-epoxy-...
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MDPI AG
2011-10-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/11/9017/ |
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| author | Yong Yan Wang Zhi Wei Deng Zhi Long Liu Shu Shan Du Peng Liu Chun Qi Bai Qi Zhi Liu Zi Mu Liu Gang Li Wang Hai Ming Zhang |
| author_facet | Yong Yan Wang Zhi Wei Deng Zhi Long Liu Shu Shan Du Peng Liu Chun Qi Bai Qi Zhi Liu Zi Mu Liu Gang Li Wang Hai Ming Zhang |
| author_sort | Yong Yan Wang |
| collection | DOAJ |
| description | The screening of several Chinese medicinal herbs for nematocidal properties showed that the ethanol extract of Liriope muscari fibrous roots possessed significant nematocidal activity against the pine wood nematode (Bursaphelenchus xylophilus). From the ethanol extract, a new constituent (1,4-epoxy-cis-eudesm-6-O-β-D-glucopyranoside) and three known glycosides [1β,6α-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside (liriopeoside A), 1β,6β-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside, and 1α,6β-dihydroxy-5,10-bis-epi-eudesm-4(15)-ene-6-O-β D-glucopyranoside] were isolated by bioassay-guided fractionation. The structures were elucidated by 1D and 2D NMR and MS techniques. 1,4-Epoxy-cis-eudesm-6-O-β-D-glucopyranoside possessed moderate nemato-cidal activity against B. xylophilus with a LC50 value of 339.76 μg/mL, while liriopeoside A (LC50 = 82.84 μg/mL) and 1β,6β-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside (LC50 = 153.39 μg/mL) also exhibited nematocidal activity against B. xylophilus. The crude extract of L. muscari fibrous roots exhibited nematocidal activity against the pine wood nematode with a LC50 value of 182.56 μg/mL. |
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| language | English |
| last_indexed | 2024-12-22T10:25:32Z |
| publishDate | 2011-10-01 |
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| series | Molecules |
| spelling | doaj.art-4a4663a2fede433cae8bcc87265a5fea2022-12-21T18:29:29ZengMDPI AGMolecules1420-30492011-10-0116119017902410.3390/molecules16119017A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous RootsYong Yan WangZhi Wei DengZhi Long LiuShu Shan DuPeng LiuChun Qi BaiQi Zhi LiuZi Mu LiuGang Li WangHai Ming ZhangThe screening of several Chinese medicinal herbs for nematocidal properties showed that the ethanol extract of Liriope muscari fibrous roots possessed significant nematocidal activity against the pine wood nematode (Bursaphelenchus xylophilus). From the ethanol extract, a new constituent (1,4-epoxy-cis-eudesm-6-O-β-D-glucopyranoside) and three known glycosides [1β,6α-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside (liriopeoside A), 1β,6β-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside, and 1α,6β-dihydroxy-5,10-bis-epi-eudesm-4(15)-ene-6-O-β D-glucopyranoside] were isolated by bioassay-guided fractionation. The structures were elucidated by 1D and 2D NMR and MS techniques. 1,4-Epoxy-cis-eudesm-6-O-β-D-glucopyranoside possessed moderate nemato-cidal activity against B. xylophilus with a LC50 value of 339.76 μg/mL, while liriopeoside A (LC50 = 82.84 μg/mL) and 1β,6β-dihydroxy-cis-eudesm-3-ene-6-O-β-D-glucopyranoside (LC50 = 153.39 μg/mL) also exhibited nematocidal activity against B. xylophilus. The crude extract of L. muscari fibrous roots exhibited nematocidal activity against the pine wood nematode with a LC50 value of 182.56 μg/mL.http://www.mdpi.com/1420-3049/16/11/9017/Liriope muscariNematocidal activityBursaphelenchus xylophilus1,4-epoxy-cis-eudesm-6-O-β-D-glucopyranoside |
| spellingShingle | Yong Yan Wang Zhi Wei Deng Zhi Long Liu Shu Shan Du Peng Liu Chun Qi Bai Qi Zhi Liu Zi Mu Liu Gang Li Wang Hai Ming Zhang A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots Molecules Liriope muscari Nematocidal activity Bursaphelenchus xylophilus 1,4-epoxy-cis-eudesm-6-O-β-D-glucopyranoside |
| title | A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots |
| title_full | A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots |
| title_fullStr | A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots |
| title_full_unstemmed | A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots |
| title_short | A New Eudesmane Sesquiterpene Glucoside from Liriope muscari Fibrous Roots |
| title_sort | new eudesmane sesquiterpene glucoside from liriope muscari fibrous roots |
| topic | Liriope muscari Nematocidal activity Bursaphelenchus xylophilus 1,4-epoxy-cis-eudesm-6-O-β-D-glucopyranoside |
| url | http://www.mdpi.com/1420-3049/16/11/9017/ |
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