Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study
Purpose: Positron Emission Tomography (PET) imaging is a nuclear medicine imaging technique based on the recording of two photons as coincidence created by positron annihilation. Materials and Methods: PET coincidence events include true and unwanted coincidences (random, scattered, multiple coincid...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2019-12-01
|
| Series: | Frontiers in Biomedical Technologies |
| Subjects: | |
| Online Access: | https://fbt.tums.ac.ir/index.php/fbt/article/view/237 |
| _version_ | 1818143228093792256 |
|---|---|
| author | Mahak Osouli Alamdari Pardis Ghafarian Parham Geramifar Mohammad Reza Ay |
| author_facet | Mahak Osouli Alamdari Pardis Ghafarian Parham Geramifar Mohammad Reza Ay |
| author_sort | Mahak Osouli Alamdari |
| collection | DOAJ |
| description | Purpose: Positron Emission Tomography (PET) imaging is a nuclear medicine imaging technique based on the recording of two photons as coincidence created by positron annihilation.
Materials and Methods: PET coincidence events include true and unwanted coincidences (random, scattered, multiple coincidences). We modeled the Discovery 690 (D-690) PET scanner using the GATE simulation tool and estimated the effect of the diameter of the scattering medium out of the Axial Field of View (AFOV) on the random coincidence rates.
Results: The validation results indicated that the average difference between simulated and measured data for sensitivity and scatter fraction tests are 5% and 3%, respectively. Moreover, the results revealed that the increasing diameter of the scattering medium out of the AFOV has a direct effect on the random coincidence rates within the Field of View (FOV).
Conclusion: The study concluded that the presence of a scattering medium near the FOV increases the rate of random coincidences. |
| first_indexed | 2024-12-11T11:28:20Z |
| format | Article |
| id | doaj.art-4a46b724552747f69aa4d4491a4c2eb0 |
| institution | Directory Open Access Journal |
| issn | 2345-5837 |
| language | English |
| last_indexed | 2024-12-11T11:28:20Z |
| publishDate | 2019-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Biomedical Technologies |
| spelling | doaj.art-4a46b724552747f69aa4d4491a4c2eb02022-12-22T01:08:56ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372019-12-016410.18502/fbt.v6i4.2211Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation StudyMahak Osouli Alamdari0Pardis Ghafarian1Parham Geramifar2Mohammad Reza Ay3Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, IranChronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IranResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran.Purpose: Positron Emission Tomography (PET) imaging is a nuclear medicine imaging technique based on the recording of two photons as coincidence created by positron annihilation. Materials and Methods: PET coincidence events include true and unwanted coincidences (random, scattered, multiple coincidences). We modeled the Discovery 690 (D-690) PET scanner using the GATE simulation tool and estimated the effect of the diameter of the scattering medium out of the Axial Field of View (AFOV) on the random coincidence rates. Results: The validation results indicated that the average difference between simulated and measured data for sensitivity and scatter fraction tests are 5% and 3%, respectively. Moreover, the results revealed that the increasing diameter of the scattering medium out of the AFOV has a direct effect on the random coincidence rates within the Field of View (FOV). Conclusion: The study concluded that the presence of a scattering medium near the FOV increases the rate of random coincidences.https://fbt.tums.ac.ir/index.php/fbt/article/view/237Positron Emission TomographyRandom CoincidencesNoise Equivalent Count RateMonte CarloScatter Medium |
| spellingShingle | Mahak Osouli Alamdari Pardis Ghafarian Parham Geramifar Mohammad Reza Ay Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study Frontiers in Biomedical Technologies Positron Emission Tomography Random Coincidences Noise Equivalent Count Rate Monte Carlo Scatter Medium |
| title | Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study |
| title_full | Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study |
| title_fullStr | Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study |
| title_full_unstemmed | Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study |
| title_short | Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study |
| title_sort | evaluation of the impact of out of axial fov scattering medium on random coincidence rates on discovery 690 pet ct scanner a simulation study |
| topic | Positron Emission Tomography Random Coincidences Noise Equivalent Count Rate Monte Carlo Scatter Medium |
| url | https://fbt.tums.ac.ir/index.php/fbt/article/view/237 |
| work_keys_str_mv | AT mahakosoulialamdari evaluationoftheimpactofoutofaxialfovscatteringmediumonrandomcoincidenceratesondiscovery690petctscannerasimulationstudy AT pardisghafarian evaluationoftheimpactofoutofaxialfovscatteringmediumonrandomcoincidenceratesondiscovery690petctscannerasimulationstudy AT parhamgeramifar evaluationoftheimpactofoutofaxialfovscatteringmediumonrandomcoincidenceratesondiscovery690petctscannerasimulationstudy AT mohammadrezaay evaluationoftheimpactofoutofaxialfovscatteringmediumonrandomcoincidenceratesondiscovery690petctscannerasimulationstudy |