Radiation Exposure Perturbs IL-17RA-Mediated Immunity Leading to Changes in Neutrophil Responses That Increase Susceptibility to Oropharyngeal Candidiasis

Radiation Exposure Perturbs IL-17RA-Mediated Immunity Leading to Changes in Neutrophil Responses That Increase Susceptibility to Oropharyngeal Candidiasis

Fungal infections caused by <i>Candida albicans</i> are a serious problem for immunocompromised individuals, including those undergoing radiotherapy for head and neck cancers. Targeted irradiation causes inflammatory dysregulation and damage to the oral mucosa that can be exacerbated by...

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Bibliographic Details
Main Authors: Jessica Saul-McBeth, John Dillon, Dylan Launder, Maura Hickey, Elise Mein-Chiain Yi, Yusuf Daboul, Priosmita Biswas, Elahheh Salari, E. Ishmael Parsai, Heather R. Conti
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Fungi
Subjects:
oral immunity
interleukin-17
candidiasis
neutrophil
antifungal
Online Access:https://www.mdpi.com/2309-608X/8/5/495

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