Phage-Displayed Peptides for Targeting Tyrosine Kinase Membrane Receptors in Cancer Therapy

Phage-Displayed Peptides for Targeting Tyrosine Kinase Membrane Receptors in Cancer Therapy

Receptor tyrosine kinases (RTKs) regulate critical physiological processes, such as cell growth, survival, motility, and metabolism. Abnormal activation of RTKs and relative downstream signaling is implicated in cancer pathogenesis. Phage display allows the rapid selection of peptide ligands of memb...

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Bibliographic Details
Main Authors: Annamaria Aloisio, Nancy Nisticò, Selena Mimmi, Domenico Maisano, Eleonora Vecchio, Giuseppe Fiume, Enrico Iaccino, Ileana Quinto
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
phage display
peptide ligands
tyrosine kinase receptors
tumor-targeting
Online Access:https://www.mdpi.com/1999-4915/13/4/649

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