Neurocutaneous Syndromes and Epilepsy
Objectives:Neurocutaneous syndromes are genetic diseases that affect the nervous system and the skin. Epileptic seizures are seen with variable frequency. In the present study, data of 29 patients from 5 centers were analyzed in an effort to draw attention to the disease group.Methods:Data of 29 pat...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2016-04-01
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| Series: | Archives of Epilepsy |
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| Online Access: |
http://archepilepsy.org/archives/archive-detail/article-preview/neurocutaneous-syndromes-and-epilepsy/55057
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| author | Abidin ERDAL Aylin BİCAN DEMİR İpek MİDİ Yasemin BİÇER GÖMCELİ Gülnihal KUTLU S. Naz YENİ İbrahim BORA |
| author_facet | Abidin ERDAL Aylin BİCAN DEMİR İpek MİDİ Yasemin BİÇER GÖMCELİ Gülnihal KUTLU S. Naz YENİ İbrahim BORA |
| author_sort | Abidin ERDAL |
| collection | DOAJ |
| description | Objectives:Neurocutaneous syndromes are genetic diseases that affect the nervous system and the skin. Epileptic seizures are seen with variable frequency. In the present study, data of 29 patients from 5 centers were analyzed in an effort to draw attention to the disease group.Methods:Data of 29 patients diagnosed with neurocutaneous syndrome were retrospectively evaluated.Results:Study population was composed of 15 women (51.7%) and 14 men (48.3%), with a mean age of 31 (72±2.16). Ten patients (34.5%) were diagnosed with tuberous sclerosis, 9 (31%) with Sturge–Weber syndrome, 3 (10.3%) with neurofibromatosis type 1, 3 (10.3%) with neurofibromatosis type 2, 1 (3.4%) with neurocutaneous melanosis, 1 (3.4%) with hypomelanosis of Ito, 1 (3.4%) with probable Sturge–Weber syndrome, and 1 patient was diagnosed with unclassified neurocutaneous syndrome. One patient did not receive antiepileptic treatment, 9 (31%) received monotherapy, and 19 (65.5%) received polytherapy. Carbamazepine was the most commonly used medication.Conclusion:Attention is drawn to the prevalence of neurocutaneous syndrome in epileptic adults, with seizure frequency depending on syndrome type. |
| first_indexed | 2024-03-12T20:38:02Z |
| format | Article |
| id | doaj.art-4a4ae5e5cee64bfc836bbbf540c9c7f8 |
| institution | Directory Open Access Journal |
| issn | 2792-0550 |
| language | English |
| last_indexed | 2024-03-12T20:38:02Z |
| publishDate | 2016-04-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Archives of Epilepsy |
| spelling | doaj.art-4a4ae5e5cee64bfc836bbbf540c9c7f82023-08-01T11:14:03ZengGalenos YayineviArchives of Epilepsy2792-05502016-04-01221121610.5505/epilepsi.2016.6363413049054Neurocutaneous Syndromes and EpilepsyAbidin ERDAL0Aylin BİCAN DEMİR1İpek MİDİ2Yasemin BİÇER GÖMCELİ3Gülnihal KUTLU4S. Naz YENİ5İbrahim BORA6 Department Of Neurology, Antalya Education And Research Hospital, Antalya, Turkey Department of Neurology, Uludağ University Faculty of Medicine, Bursa, Turkey Department Of Neurology, Marmara University Medical School, İstanbul, Turkey Department Of Neurology, Antalya Education And Research Hospital, Antalya, Turkey Department Of Neurology, Muğla Sk University Medical School, Muğla, Turkey Department Of Neurology, İstanbul University Cerrahpaşa Medical School, İstanbul, Turkey Department of Neurology, Uludağ University Faculty of Medicine, Bursa, Turkey Objectives:Neurocutaneous syndromes are genetic diseases that affect the nervous system and the skin. Epileptic seizures are seen with variable frequency. In the present study, data of 29 patients from 5 centers were analyzed in an effort to draw attention to the disease group.Methods:Data of 29 patients diagnosed with neurocutaneous syndrome were retrospectively evaluated.Results:Study population was composed of 15 women (51.7%) and 14 men (48.3%), with a mean age of 31 (72±2.16). Ten patients (34.5%) were diagnosed with tuberous sclerosis, 9 (31%) with Sturge–Weber syndrome, 3 (10.3%) with neurofibromatosis type 1, 3 (10.3%) with neurofibromatosis type 2, 1 (3.4%) with neurocutaneous melanosis, 1 (3.4%) with hypomelanosis of Ito, 1 (3.4%) with probable Sturge–Weber syndrome, and 1 patient was diagnosed with unclassified neurocutaneous syndrome. One patient did not receive antiepileptic treatment, 9 (31%) received monotherapy, and 19 (65.5%) received polytherapy. Carbamazepine was the most commonly used medication.Conclusion:Attention is drawn to the prevalence of neurocutaneous syndrome in epileptic adults, with seizure frequency depending on syndrome type. http://archepilepsy.org/archives/archive-detail/article-preview/neurocutaneous-syndromes-and-epilepsy/55057 epilepsyseizureneurocutaneous syndromes |
| spellingShingle | Abidin ERDAL Aylin BİCAN DEMİR İpek MİDİ Yasemin BİÇER GÖMCELİ Gülnihal KUTLU S. Naz YENİ İbrahim BORA Neurocutaneous Syndromes and Epilepsy Archives of Epilepsy epilepsy seizure neurocutaneous syndromes |
| title | Neurocutaneous Syndromes and Epilepsy |
| title_full | Neurocutaneous Syndromes and Epilepsy |
| title_fullStr | Neurocutaneous Syndromes and Epilepsy |
| title_full_unstemmed | Neurocutaneous Syndromes and Epilepsy |
| title_short | Neurocutaneous Syndromes and Epilepsy |
| title_sort | neurocutaneous syndromes and epilepsy |
| topic | epilepsy seizure neurocutaneous syndromes |
| url |
http://archepilepsy.org/archives/archive-detail/article-preview/neurocutaneous-syndromes-and-epilepsy/55057
|
| work_keys_str_mv | AT abidinerdal neurocutaneoussyndromesandepilepsy AT aylinbicandemir neurocutaneoussyndromesandepilepsy AT ipekmidi neurocutaneoussyndromesandepilepsy AT yaseminbicergomceli neurocutaneoussyndromesandepilepsy AT gulnihalkutlu neurocutaneoussyndromesandepilepsy AT snazyeni neurocutaneoussyndromesandepilepsy AT ibrahimbora neurocutaneoussyndromesandepilepsy |