Prognostic Markers and Driver Genes and Options for Targeted Therapy in Human-Papillomavirus-Positive Tonsillar and Base-of-Tongue Squamous Cell Carcinoma

Prognostic Markers and Driver Genes and Options for Targeted Therapy in Human-Papillomavirus-Positive Tonsillar and Base-of-Tongue Squamous Cell Carcinoma

The incidence of Human-papillomavirus-positive (HPV<sup>+</sup>) tonsillar and base-of-tongue squamous cell carcinoma (TSCC and BOTSCC, respectively) is increasing epidemically, but they have better prognosis than equivalent HPV-negative (HPV<sup>−</sup>) cancers, with roughl...

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Bibliographic Details
Main Authors: Anders Näsman, Stefan Holzhauser, Ourania N. Kostopoulou, Mark Zupancic, Andreas Ährlund-Richter, Juan Du, Tina Dalianis
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
human papillomavirus
tonsillar squamous cell carcinoma
base-of-tongue squamous cell carcinoma
oropharyngeal squamous cell carcinoma
mutations
prognostic marker
Online Access:https://www.mdpi.com/1999-4915/13/5/910

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