The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report
Background and objectives: Ventricular fibrillation occurring in a patient can result in unexpected complications. Here, our aim is to present a case of ventricular fibrillation occurring immediately after anesthesia induction with etomidate administration. Case report: A fifty-six-year-old female p...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014-09-01
|
Series: | Brazilian Journal of Anesthesiology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0104001413001486 |
_version_ | 1811203132834709504 |
---|---|
author | Murat Karcioglu Isil Davarci Nuray Kirecci Adnan Burak Akcay Selim Turhanoglu Kasim Tuzcu Sedat Hakimoglu Seckin Akkucuk Akin Aydogan |
author_facet | Murat Karcioglu Isil Davarci Nuray Kirecci Adnan Burak Akcay Selim Turhanoglu Kasim Tuzcu Sedat Hakimoglu Seckin Akkucuk Akin Aydogan |
author_sort | Murat Karcioglu |
collection | DOAJ |
description | Background and objectives: Ventricular fibrillation occurring in a patient can result in unexpected complications. Here, our aim is to present a case of ventricular fibrillation occurring immediately after anesthesia induction with etomidate administration. Case report: A fifty-six-year-old female patient with a pre-diagnosis of gallstones was admitted to the operating room for laparoscopic cholecystectomy. The induction was performed by etomidate with a bolus dose of 0.3 mg/kg. Severe and fast adduction appeared in the patient's arms immediately after induction. A tachycardia with wide QRS and ventricular rate 188 beat/min was detected on the monitor. The rhythm turned to VF during the preparation of cardioversion. Immediately we performed defibrillation to the patient. Sinus rhythm was obtained. It was decided to postpone the operation due to the patient's unstable condition. Conclusion: In addition to other known side effects of etomidate, very rarely, ventricular tachycardia and fibrillation can be also seen. To the best of our knowledge, this is the first case regarding etomidate causing VF in the literature. Resumo: Justificativa e objetivos: A ocorrência de fibrilação ventricular em um paciente pode resultar em complicações inesperadas. Nosso objetivo é apresentar um caso de fibrilação ventricular que ocorreu após a indução anestésica com administração de etomidato. Relato de caso: Paciente do sexo feminino, 56 anos, com pré-diagnóstico de cálculos biliares, foi admitida na sala de cirurgia para colecistectomia laparoscópica. A anestesia foi induzida com a administração de etomidato com uma dose em bolus de 0,3 mg/kg. A paciente apresentou uma grave e rápida adução dos braços logo após a indução. Taquicardia com QRS largo e frequência ventricular de 188 bpm foram detectadas no monitor. O ritmo converteu-se em fibrilação ventricular (FV) durante a preparação para a cardioversão. A paciente foi imediatamente submetida a desfibrilação. O ritmo sinusal foi obtido. Decidimos adiar a cirurgia por causa da condição de instabilidade da paciente. Conclusão: Além dos efeitos secundários conhecidos de etomidato, taquicardia ventricular e fibrilação, embora muito raramente, também podem ser observadas. Até onde sabemos, esse é o primeiro caso na literatura de FV causado por etomidato. Keywords: Etomidate, Induction of anesthesia, Ventricular fibrillation, Palavras-chave: Etomidato, Indução da anestesia, Fibrilação ventricular |
first_indexed | 2024-04-12T02:50:34Z |
format | Article |
id | doaj.art-4a51bb622c3d4ba491e299b807ee5fce |
institution | Directory Open Access Journal |
issn | 0104-0014 |
language | English |
last_indexed | 2024-04-12T02:50:34Z |
publishDate | 2014-09-01 |
publisher | Elsevier |
record_format | Article |
series | Brazilian Journal of Anesthesiology |
spelling | doaj.art-4a51bb622c3d4ba491e299b807ee5fce2022-12-22T03:51:00ZengElsevierBrazilian Journal of Anesthesiology0104-00142014-09-01645365368The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case reportMurat Karcioglu0Isil Davarci1Nuray Kirecci2Adnan Burak Akcay3Selim Turhanoglu4Kasim Tuzcu5Sedat Hakimoglu6Seckin Akkucuk7Akin Aydogan8Department of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey; Corresponding author.Department of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of Cardiology, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of General Surgery, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyDepartment of General Surgery, Faculty of Medicine, Mustafa Kemal University, Hatay, TurkeyBackground and objectives: Ventricular fibrillation occurring in a patient can result in unexpected complications. Here, our aim is to present a case of ventricular fibrillation occurring immediately after anesthesia induction with etomidate administration. Case report: A fifty-six-year-old female patient with a pre-diagnosis of gallstones was admitted to the operating room for laparoscopic cholecystectomy. The induction was performed by etomidate with a bolus dose of 0.3 mg/kg. Severe and fast adduction appeared in the patient's arms immediately after induction. A tachycardia with wide QRS and ventricular rate 188 beat/min was detected on the monitor. The rhythm turned to VF during the preparation of cardioversion. Immediately we performed defibrillation to the patient. Sinus rhythm was obtained. It was decided to postpone the operation due to the patient's unstable condition. Conclusion: In addition to other known side effects of etomidate, very rarely, ventricular tachycardia and fibrillation can be also seen. To the best of our knowledge, this is the first case regarding etomidate causing VF in the literature. Resumo: Justificativa e objetivos: A ocorrência de fibrilação ventricular em um paciente pode resultar em complicações inesperadas. Nosso objetivo é apresentar um caso de fibrilação ventricular que ocorreu após a indução anestésica com administração de etomidato. Relato de caso: Paciente do sexo feminino, 56 anos, com pré-diagnóstico de cálculos biliares, foi admitida na sala de cirurgia para colecistectomia laparoscópica. A anestesia foi induzida com a administração de etomidato com uma dose em bolus de 0,3 mg/kg. A paciente apresentou uma grave e rápida adução dos braços logo após a indução. Taquicardia com QRS largo e frequência ventricular de 188 bpm foram detectadas no monitor. O ritmo converteu-se em fibrilação ventricular (FV) durante a preparação para a cardioversão. A paciente foi imediatamente submetida a desfibrilação. O ritmo sinusal foi obtido. Decidimos adiar a cirurgia por causa da condição de instabilidade da paciente. Conclusão: Além dos efeitos secundários conhecidos de etomidato, taquicardia ventricular e fibrilação, embora muito raramente, também podem ser observadas. Até onde sabemos, esse é o primeiro caso na literatura de FV causado por etomidato. Keywords: Etomidate, Induction of anesthesia, Ventricular fibrillation, Palavras-chave: Etomidato, Indução da anestesia, Fibrilação ventricularhttp://www.sciencedirect.com/science/article/pii/S0104001413001486 |
spellingShingle | Murat Karcioglu Isil Davarci Nuray Kirecci Adnan Burak Akcay Selim Turhanoglu Kasim Tuzcu Sedat Hakimoglu Seckin Akkucuk Akin Aydogan The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report Brazilian Journal of Anesthesiology |
title | The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report |
title_full | The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report |
title_fullStr | The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report |
title_full_unstemmed | The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report |
title_short | The development of ventricular fibrillation due to etomidate for anesthetic induction: a very rare side effect, case report |
title_sort | development of ventricular fibrillation due to etomidate for anesthetic induction a very rare side effect case report |
url | http://www.sciencedirect.com/science/article/pii/S0104001413001486 |
work_keys_str_mv | AT muratkarcioglu thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT isildavarci thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT nuraykirecci thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT adnanburakakcay thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT selimturhanoglu thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT kasimtuzcu thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT sedathakimoglu thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT seckinakkucuk thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT akinaydogan thedevelopmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT muratkarcioglu developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT isildavarci developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT nuraykirecci developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT adnanburakakcay developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT selimturhanoglu developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT kasimtuzcu developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT sedathakimoglu developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT seckinakkucuk developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport AT akinaydogan developmentofventricularfibrillationduetoetomidateforanestheticinductionaveryraresideeffectcasereport |