Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections
Conventional treatments fail to completely eradicate tumor or bacterial infections due to their inherent shortcomings. In recent years, photothermal therapy (PTT) has emerged as an attractive treatment modality that relies on the absorption of photothermal agents (PTAs) at a specific wavelength, the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/7/3/94 |
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| author | Chiranjeevi Korupalli Poliraju Kalluru Karthik Nuthalapati Naresh Kuthala Suresh Thangudu Raviraj Vankayala |
| author_facet | Chiranjeevi Korupalli Poliraju Kalluru Karthik Nuthalapati Naresh Kuthala Suresh Thangudu Raviraj Vankayala |
| author_sort | Chiranjeevi Korupalli |
| collection | DOAJ |
| description | Conventional treatments fail to completely eradicate tumor or bacterial infections due to their inherent shortcomings. In recent years, photothermal therapy (PTT) has emerged as an attractive treatment modality that relies on the absorption of photothermal agents (PTAs) at a specific wavelength, thereby transforming the excitation light energy into heat. The advantages of PTT are its high efficacy, specificity, and minimal damage to normal tissues. To this end, various inorganic nanomaterials such as gold nanostructures, carbon nanostructures, and transition metal dichalcogenides have been extensively explored for PTT applications. Subsequently, the focus has shifted to the development of polymeric PTAs, owing to their unique properties such as biodegradability, biocompatibility, non-immunogenicity, and low toxicity when compared to inorganic PTAs. Among various organic PTAs, polyaniline (PANI) is one of the best-known and earliest-reported organic PTAs. Hence, in this review, we cover the recent advances and progress of PANI-based biomaterials for PTT application in tumors and bacterial infections. The future prospects in this exciting area are also addressed. |
| first_indexed | 2024-03-10T17:31:29Z |
| format | Article |
| id | doaj.art-4a55bce193b44c4d85c77415a26f8683 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-10T17:31:29Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-4a55bce193b44c4d85c77415a26f86832023-11-20T10:00:47ZengMDPI AGBioengineering2306-53542020-08-01739410.3390/bioengineering7030094Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial InfectionsChiranjeevi Korupalli0Poliraju Kalluru1Karthik Nuthalapati2Naresh Kuthala3Suresh Thangudu4Raviraj Vankayala5Department of Chemical Engineering, National Tsing Hua University, Hsinchu 30013, TaiwanDepartment of Chemistry, University of Calgary, Calgary, AB T2N1N4, CanadaDepartment of Chemistry, National Tsing Hua University, Hsinchu 30013, TaiwanDepartment of Chemistry, National Tsing Hua University, Hsinchu 30013, TaiwanDepartment of Chemistry, National Tsing Hua University, Hsinchu 30013, TaiwanDepartment of Bioscience and Bioengineering, Indian Institute of Technology Jodhpur, Jodhpur, Rajasthan 342037, IndiaConventional treatments fail to completely eradicate tumor or bacterial infections due to their inherent shortcomings. In recent years, photothermal therapy (PTT) has emerged as an attractive treatment modality that relies on the absorption of photothermal agents (PTAs) at a specific wavelength, thereby transforming the excitation light energy into heat. The advantages of PTT are its high efficacy, specificity, and minimal damage to normal tissues. To this end, various inorganic nanomaterials such as gold nanostructures, carbon nanostructures, and transition metal dichalcogenides have been extensively explored for PTT applications. Subsequently, the focus has shifted to the development of polymeric PTAs, owing to their unique properties such as biodegradability, biocompatibility, non-immunogenicity, and low toxicity when compared to inorganic PTAs. Among various organic PTAs, polyaniline (PANI) is one of the best-known and earliest-reported organic PTAs. Hence, in this review, we cover the recent advances and progress of PANI-based biomaterials for PTT application in tumors and bacterial infections. The future prospects in this exciting area are also addressed.https://www.mdpi.com/2306-5354/7/3/94polyanilinephotothermal therapycancerbacteria |
| spellingShingle | Chiranjeevi Korupalli Poliraju Kalluru Karthik Nuthalapati Naresh Kuthala Suresh Thangudu Raviraj Vankayala Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections Bioengineering polyaniline photothermal therapy cancer bacteria |
| title | Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections |
| title_full | Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections |
| title_fullStr | Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections |
| title_full_unstemmed | Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections |
| title_short | Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections |
| title_sort | recent advances of polyaniline based biomaterials for phototherapeutic treatments of tumors and bacterial infections |
| topic | polyaniline photothermal therapy cancer bacteria |
| url | https://www.mdpi.com/2306-5354/7/3/94 |
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