The Muscarinic Acetylcholine M<sub>2</sub> Receptor-Induced Nitration of p190A by eNOS Increases RhoA Activity in Cardiac Myocytes

The Muscarinic Acetylcholine M<sub>2</sub> Receptor-Induced Nitration of p190A by eNOS Increases RhoA Activity in Cardiac Myocytes

p190RhoGAP, which exists in two paralogs, p190RhoGAP-A (p190A) and p190RhoGAP-B (p190B), is a GTPase activating protein (GAP) contributing to the regulation of the cellular activity of RhoGTPases. Recent data showed that M<sub>2</sub> muscarinic acetylcholine receptor (M<sub>2</...

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Bibliographic Details
Main Authors: Magdolna K. Levay, Lena Throm, Nabil Bahrami, Thomas Wieland
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
muscarinic acetylcholine receptor (MR)
endothelial nitric oxide synthase (eNOS)
caveolin-3 (Cav3)
p190RhoGAP
p190A
p190B
Online Access:https://www.mdpi.com/2073-4409/12/20/2432

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