Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins

Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins

Phospholipid transfer protein gene knock-out (Pltp KO) mice have defective transfer of very low density lipoprotein (VLDL) phospholipids into high density lipoprotein (HDL) and markedly decreased HDL levels (Jiang et al. 1999. J. Clin. Invest. 103: 907–914). These animals also accumulated VLDL- and...

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Bibliographic Details
Main Authors: Shucun Qin, Koichi Kawano, Can Bruce, Min Lin, Charles Bisgaier, Alan R. Tall, Xian-cheng Jiang
Format: Article
Language:English
Published: Elsevier 2000-02-01
Series:Journal of Lipid Research
Subjects:
HDL
lipoproteins
apolipoproteins
phospholipids
fractional catabolic rate
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320617

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