Progress in drug delivery and diagnostic applications of carbon dots: a systematic review
Carbon dots (CDs), which have particle size of less than 10 nm, are carbon-based nanomaterials that are used in a wide range of applications in the area of novel drug delivery in cancer, ocular diseases, infectious diseases, and brain disorders. CDs are biocompatible, eco-friendly, easy to synthesiz...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2023.1227843/full |
| _version_ | 1797780088265113600 |
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| author | Hemlata Kaurav Dhriti Verma Amit Bansal Deepak N. Kapoor Sandeep Sheth |
| author_facet | Hemlata Kaurav Dhriti Verma Amit Bansal Deepak N. Kapoor Sandeep Sheth |
| author_sort | Hemlata Kaurav |
| collection | DOAJ |
| description | Carbon dots (CDs), which have particle size of less than 10 nm, are carbon-based nanomaterials that are used in a wide range of applications in the area of novel drug delivery in cancer, ocular diseases, infectious diseases, and brain disorders. CDs are biocompatible, eco-friendly, easy to synthesize, and less toxic with excellent chemical inertness, which makes them very good nanocarrier system to deliver multi-functional drugs effectively. A huge number of researchers worldwide are working on CDs-based drug delivery systems to evaluate their versatility and efficacy in the field of pharmaceuticals. As a result, there is a tremendous increase in our understanding of the physicochemical properties, diagnostic and drug delivery aspects of CDs, which consequently has led us to design and develop CDs-based theranostic system for the treatment of multiple disorders. In this review, we aim to summarize the advances in application of CDs as nanocarrier including gene delivery, vaccine delivery and antiviral delivery, that has been carried out in the last 5 years. |
| first_indexed | 2024-03-12T23:39:35Z |
| format | Article |
| id | doaj.art-4a5f3e26a08241e984b3423c881078f2 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-03-12T23:39:35Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-4a5f3e26a08241e984b3423c881078f22023-07-14T23:08:12ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462023-07-011110.3389/fchem.2023.12278431227843Progress in drug delivery and diagnostic applications of carbon dots: a systematic reviewHemlata Kaurav0Dhriti Verma1Amit Bansal2Deepak N. Kapoor3Sandeep Sheth4School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, IndiaSchool of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, IndiaFormulation Research and Development, Perrigo Company Plc, Allegan, MI, United StatesSchool of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, IndiaDepartment of Pharmaceutical Sciences, College of Pharmacy, Larkin University, Miami, FL, United StatesCarbon dots (CDs), which have particle size of less than 10 nm, are carbon-based nanomaterials that are used in a wide range of applications in the area of novel drug delivery in cancer, ocular diseases, infectious diseases, and brain disorders. CDs are biocompatible, eco-friendly, easy to synthesize, and less toxic with excellent chemical inertness, which makes them very good nanocarrier system to deliver multi-functional drugs effectively. A huge number of researchers worldwide are working on CDs-based drug delivery systems to evaluate their versatility and efficacy in the field of pharmaceuticals. As a result, there is a tremendous increase in our understanding of the physicochemical properties, diagnostic and drug delivery aspects of CDs, which consequently has led us to design and develop CDs-based theranostic system for the treatment of multiple disorders. In this review, we aim to summarize the advances in application of CDs as nanocarrier including gene delivery, vaccine delivery and antiviral delivery, that has been carried out in the last 5 years.https://www.frontiersin.org/articles/10.3389/fchem.2023.1227843/fullcarbon dotsdrug deliverygene deliverynanocarriersbioimaging |
| spellingShingle | Hemlata Kaurav Dhriti Verma Amit Bansal Deepak N. Kapoor Sandeep Sheth Progress in drug delivery and diagnostic applications of carbon dots: a systematic review Frontiers in Chemistry carbon dots drug delivery gene delivery nanocarriers bioimaging |
| title | Progress in drug delivery and diagnostic applications of carbon dots: a systematic review |
| title_full | Progress in drug delivery and diagnostic applications of carbon dots: a systematic review |
| title_fullStr | Progress in drug delivery and diagnostic applications of carbon dots: a systematic review |
| title_full_unstemmed | Progress in drug delivery and diagnostic applications of carbon dots: a systematic review |
| title_short | Progress in drug delivery and diagnostic applications of carbon dots: a systematic review |
| title_sort | progress in drug delivery and diagnostic applications of carbon dots a systematic review |
| topic | carbon dots drug delivery gene delivery nanocarriers bioimaging |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2023.1227843/full |
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