Long pentraxin 3 and vitamin D receptor mRNA expression pattern of cumulus granulosa cells isolated from PCOS oocytes at different stages of nuclear maturation

Long pentraxin 3 and vitamin D receptor mRNA expression pattern of cumulus granulosa cells isolated from PCOS oocytes at different stages of nuclear maturation

Abstract Background A fine-tuned pro-inflammatory and anti-inflammatory balance in the follicular unit is essential for cumulus expansion and successful ovulation. While the long pentraxin 3 (PTX3) gene is required for the expansion of cumulus cells (CCs), ovulation, resumption of meiosis and fertil...

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Main Authors: Aynur Ersahin, Onder Celik, Nur D. Gungor, Nilufer Celik, Sureyya Melil, Meltem Yardim, Semih Dalkilic, Cenk Ersahin, Ece Dogukargin, Sudenaz Celik, Ramazan F. Akkoc
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Reproductive Biology and Endocrinology
Subjects:
Polycystic ovary syndrome
Cumulus expansion
VDR, PTX3, fertilization
Online Access:https://doi.org/10.1186/s12958-023-01176-5

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