Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity
The aim of this study was to investigate the effects of 12 weeks of high-intensity training with astaxanthin supplementation on adipokine levels, insulin resistance and lipid profiles in males with obesity. Sixty-eight males with obesity were randomly stratified into four groups of seventeen subject...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/2/286 |
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| author | Ayoub Saeidi Akbar Nouri-Habashi Omid Razi Ali Ataeinosrat Hiwa Rahmani Shirin Shirzad Mollabashi Behnam Bagherzadeh-Rahmani Shahin Mahmoudi Aghdam Leila Khalajzadeh Maisa Hamed Al Kiyumi Anthony C. Hackney Ismail Laher Katie M. Heinrich Hassane Zouhal |
| author_facet | Ayoub Saeidi Akbar Nouri-Habashi Omid Razi Ali Ataeinosrat Hiwa Rahmani Shirin Shirzad Mollabashi Behnam Bagherzadeh-Rahmani Shahin Mahmoudi Aghdam Leila Khalajzadeh Maisa Hamed Al Kiyumi Anthony C. Hackney Ismail Laher Katie M. Heinrich Hassane Zouhal |
| author_sort | Ayoub Saeidi |
| collection | DOAJ |
| description | The aim of this study was to investigate the effects of 12 weeks of high-intensity training with astaxanthin supplementation on adipokine levels, insulin resistance and lipid profiles in males with obesity. Sixty-eight males with obesity were randomly stratified into four groups of seventeen subjects each: control group (CG), supplement group (SG), training group (TG), and training plus supplement group (TSG). Participants underwent 12 weeks of treatment with astaxanthin or placebo (20 mg/d capsule daily). The training protocol consisted of 36 sessions of high-intensity functional training (HIFT), 60 min/sessions, and three sessions/week. Metabolic profiles, body composition, anthropometrical measurements, cardio-respiratory indices and adipokine [Cq1/TNF-related protein 9 and 2 (CTRP9 and CTRP2) levels, and growth differentiation factors 8 and 15 (GDF8 and GDF15)] were measured. There were significant differences for all indicators between the groups (<i>p</i> < 0.05). Post-hoc analysis indicated that the levels of CTRP9, CTRP2, and GDF8 were different from CG (<i>p</i> < 0.05), although levels of GDF15 were similar to CG (<i>p</i> > 0.05). Levels of GDF8 were similar in the SG and TG groups (<i>p</i> > 0.05), with reductions of GDF15 levels in both training groups (<i>p</i> < 0.05). A total of 12 weeks of astaxanthin supplementation and exercise training decreased adipokines levels, body composition (weight, %fat), anthropometrical factors (BMI), and improved lipid and metabolic profiles. These benefits were greater for men with obesity in the TSG group. |
| first_indexed | 2024-03-09T11:31:26Z |
| format | Article |
| id | doaj.art-4a6194cdd6df4df089e4bf3045412953 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T11:31:26Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-4a6194cdd6df4df089e4bf30454129532023-11-30T23:49:28ZengMDPI AGNutrients2072-66432023-01-0115228610.3390/nu15020286Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with ObesityAyoub Saeidi0Akbar Nouri-Habashi1Omid Razi2Ali Ataeinosrat3Hiwa Rahmani4Shirin Shirzad Mollabashi5Behnam Bagherzadeh-Rahmani6Shahin Mahmoudi Aghdam7Leila Khalajzadeh8Maisa Hamed Al Kiyumi9Anthony C. Hackney10Ismail Laher11Katie M. Heinrich12Hassane Zouhal13Department of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj 66177-15175, IranDepartment of Exercise Physiology and Corrective Movements, Faculty of Sport Sciences, Urmia University, Urmia 57561-51818, IranDepartment of Exercise Physiology, Faculty of Physical Education and Sports Science, Razi University, Kermanshah 94Q5+6G3, IranDepartment of Physical Education and Sport Science, Science and Research Branch, Islamic Azad University, Tehran 14778-93855, IranFaculty of Physical Education and Sports Science, Alzahra University, Tehran 19938 93973, IranFaculty of Sport Sciences, Atatürk University, Erzurum 25030, TurkeyDepartment of Exercise Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar M3J+373, IranDepartment of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran 14778-93855, IranDepartment of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran 14778-93855, IranDepartment of Family Medicine and Public Health, Sultan Qaboos University Hospital, Muscat H5QC+36M, OmanDepartment of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC 27599, USADepartment of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, BC V6T 1Z4, CanadaDepartment of Kinesiology, College of Health and Human Sciences, Kansas State University, Manhattan, KS 66506, USALaboratoire Mouvement, Sport, Santé, University of Rennes, M2S—EA 1274, 35000 Rennes, FranceThe aim of this study was to investigate the effects of 12 weeks of high-intensity training with astaxanthin supplementation on adipokine levels, insulin resistance and lipid profiles in males with obesity. Sixty-eight males with obesity were randomly stratified into four groups of seventeen subjects each: control group (CG), supplement group (SG), training group (TG), and training plus supplement group (TSG). Participants underwent 12 weeks of treatment with astaxanthin or placebo (20 mg/d capsule daily). The training protocol consisted of 36 sessions of high-intensity functional training (HIFT), 60 min/sessions, and three sessions/week. Metabolic profiles, body composition, anthropometrical measurements, cardio-respiratory indices and adipokine [Cq1/TNF-related protein 9 and 2 (CTRP9 and CTRP2) levels, and growth differentiation factors 8 and 15 (GDF8 and GDF15)] were measured. There were significant differences for all indicators between the groups (<i>p</i> < 0.05). Post-hoc analysis indicated that the levels of CTRP9, CTRP2, and GDF8 were different from CG (<i>p</i> < 0.05), although levels of GDF15 were similar to CG (<i>p</i> > 0.05). Levels of GDF8 were similar in the SG and TG groups (<i>p</i> > 0.05), with reductions of GDF15 levels in both training groups (<i>p</i> < 0.05). A total of 12 weeks of astaxanthin supplementation and exercise training decreased adipokines levels, body composition (weight, %fat), anthropometrical factors (BMI), and improved lipid and metabolic profiles. These benefits were greater for men with obesity in the TSG group.https://www.mdpi.com/2072-6643/15/2/286high-intensity trainingastaxanthinadipokinescardiovascular risk factorsobesity |
| spellingShingle | Ayoub Saeidi Akbar Nouri-Habashi Omid Razi Ali Ataeinosrat Hiwa Rahmani Shirin Shirzad Mollabashi Behnam Bagherzadeh-Rahmani Shahin Mahmoudi Aghdam Leila Khalajzadeh Maisa Hamed Al Kiyumi Anthony C. Hackney Ismail Laher Katie M. Heinrich Hassane Zouhal Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity Nutrients high-intensity training astaxanthin adipokines cardiovascular risk factors obesity |
| title | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| title_full | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| title_fullStr | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| title_full_unstemmed | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| title_short | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| title_sort | astaxanthin supplemented with high intensity functional training decreases adipokines levels and cardiovascular risk factors in men with obesity |
| topic | high-intensity training astaxanthin adipokines cardiovascular risk factors obesity |
| url | https://www.mdpi.com/2072-6643/15/2/286 |
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