Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
Skin aging is a complex process that causes morphologic variations. Some of these variations have been hypothesized to be involved in skin cancer development. This paper reviews current knowledge of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Mattioli1885
2021-05-01
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| Series: | Dermatology Practical & Conceptual |
| Subjects: | |
| Online Access: | http://dpcj.org/index.php/dpc/article/view/1620 |
| _version_ | 1828140692280442880 |
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| author | Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo |
| author_facet | Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo |
| author_sort | Stefania Guida |
| collection | DOAJ |
| description | Skin aging is a complex process that causes morphologic variations. Some of these variations have
been hypothesized to be involved in skin cancer development. This paper reviews current knowledge
of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of
the technique are described, and the RCM features of healthy skin and skin cancer are briefly discussed.
Moreover, the RCM features at different layers of young and elderly skin are described, as are
the variations that occur with passing years and in relation to sun exposure that contribute to photoaging
and the development of skin cancer. RCM enables the noninvasive evaluation, at quasi-histologic
resolution, of aging-related skin changes, some of which are shared with skin cancer; this ability helps
avoid skin biopsy. Further research is needed to understand the relation between skin aging and skin
cancer development. |
| first_indexed | 2024-04-11T19:13:14Z |
| format | Article |
| id | doaj.art-4a6210cdd9ca4b6daa100af49aeba206 |
| institution | Directory Open Access Journal |
| issn | 2160-9381 |
| language | English |
| last_indexed | 2024-04-11T19:13:14Z |
| publishDate | 2021-05-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Dermatology Practical & Conceptual |
| spelling | doaj.art-4a6210cdd9ca4b6daa100af49aeba2062022-12-22T04:07:30ZengMattioli1885Dermatology Practical & Conceptual2160-93812021-05-0110.5826/dpc.1103a68Reflectance Confocal Microscopy of Aging Skin and Skin CancerStefania Guida0Giovanni Pellacani1Silvana Ciardo2Caterina Longo3Dermatology UnitUniversity of Modena and Reggio EmiliaModena, ItalyDermatology Unit, Department of Surgical, Medical, Dental and Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Italy; Dermatologic Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.Dermatology Unit, Department of Surgical, Medical, Dental and Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, ItalyDermatology Unit, Department of Surgical, Medical, Dental and Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Italy; Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale-Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia, Reggio Emilia, ItalySkin aging is a complex process that causes morphologic variations. Some of these variations have been hypothesized to be involved in skin cancer development. This paper reviews current knowledge of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of the technique are described, and the RCM features of healthy skin and skin cancer are briefly discussed. Moreover, the RCM features at different layers of young and elderly skin are described, as are the variations that occur with passing years and in relation to sun exposure that contribute to photoaging and the development of skin cancer. RCM enables the noninvasive evaluation, at quasi-histologic resolution, of aging-related skin changes, some of which are shared with skin cancer; this ability helps avoid skin biopsy. Further research is needed to understand the relation between skin aging and skin cancer development.http://dpcj.org/index.php/dpc/article/view/1620Skin agingskin cancercollagenblood vesselsreflectance confocal microscopy |
| spellingShingle | Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo Reflectance Confocal Microscopy of Aging Skin and Skin Cancer Dermatology Practical & Conceptual Skin aging skin cancer collagen blood vessels reflectance confocal microscopy |
| title | Reflectance Confocal Microscopy of Aging Skin and Skin Cancer |
| title_full | Reflectance Confocal Microscopy of Aging Skin and Skin Cancer |
| title_fullStr | Reflectance Confocal Microscopy of Aging Skin and Skin Cancer |
| title_full_unstemmed | Reflectance Confocal Microscopy of Aging Skin and Skin Cancer |
| title_short | Reflectance Confocal Microscopy of Aging Skin and Skin Cancer |
| title_sort | reflectance confocal microscopy of aging skin and skin cancer |
| topic | Skin aging skin cancer collagen blood vessels reflectance confocal microscopy |
| url | http://dpcj.org/index.php/dpc/article/view/1620 |
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