Impaired Neurofilament Integrity and Neuronal Morphology in Different Models of Focal Cerebral Ischemia and Human Stroke Tissue

Impaired Neurofilament Integrity and Neuronal Morphology in Different Models of Focal Cerebral Ischemia and Human Stroke Tissue

As part of the neuronal cytoskeleton, neurofilaments are involved in maintaining cellular integrity. In the setting of ischemic stroke, the affection of the neurofilament network is considered to mediate the transition towards long-lasting tissue damage. Although peripheral levels of distinct neurof...

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Bibliographic Details
Main Authors: Bianca Mages, Susanne Aleithe, Stephan Altmann, Alexandra Blietz, Björn Nitzsche, Henryk Barthel, Anja K. E. Horn, Constance Hobusch, Wolfgang Härtig, Martin Krueger, Dominik Michalski
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebral ischemia
stroke
MCAO
neurofilaments
α-internexin
axonal spheroids
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00161/full

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