Synuclein Proteins in MPTP-Induced Death of Substantia Nigra Pars Compacta Dopaminergic Neurons

Synuclein Proteins in MPTP-Induced Death of Substantia Nigra Pars Compacta Dopaminergic Neurons

Parkinson’s disease (PD) is one of the key neurodegenerative disorders caused by a dopamine deficiency in the striatum due to the death of dopaminergic (DA) neurons of the substantia nigra pars compacta. The initially discovered A53T mutation in the alpha-synuclein gene was linked to the formation o...

Full description

Bibliographic Details
Main Authors: Valeria V. Goloborshcheva, Valerian G. Kucheryanu, Natalia A. Voronina, Ekaterina V. Teterina, Aleksey A. Ustyugov, Sergei G. Morozov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
synucleins
dopaminergic neuron
MPTP
knockout mice
Parkinson’s disease
Online Access:https://www.mdpi.com/2227-9059/10/9/2278

Similar Items

Similar Items