High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

In the era of targeted therapy, mutation profiling of cancer is a crucial aspect of making therapeutic decisions. To characterize cancer at a molecular level, the use of formalin-fixed paraffin-embedded tissue is important. We tested the Ion AmpliSeq Cancer Hotspot Panel v2 and nCounter Copy Number...

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Bibliographic Details
Main Authors: Seokhwi Kim, Jeeyun Lee, Min Eui Hong, In-Gu Do, So Young Kang, Sang Yun Ha, Seung Tae Kim, Se Hoon Park, Won Ki Kang, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Duk-Hwan Kim, Kyoung-Mee Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4221102?pdf=render

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