Serum Uric Acid Level and Multiple Sclerosis: A Mendelian Randomization Study

Serum Uric Acid Level and Multiple Sclerosis: A Mendelian Randomization Study

Previous observational studies have shown that the serum uric acid (UA) level is decreased in persons with multiple sclerosis (MS). We used the two-sample Mendelian randomization (MR) method to determine whether the serum UA level is causally associated with the risk of MS. We screened 26 single-nuc...

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Bibliographic Details
Main Authors: Peng-Peng Niu, Bo Song, Xue Wang, Yu-Ming Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
multiple sclerosis
uric acid
mendelian randomization analysis
single-nucleotide polymorphism
causality
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00254/full

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