Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review

<p class="first" id="d17685867e265"> <b>Background:</b> Implantable cardioverter-defibrillators (ICDs) can be life-saving devices, although they are expensive and may cause complications. In 2013, several professional societi...

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Main Authors: Nikhil H. Shah, Steven J. Ross, Steve A. Noutong Njapo, Justin Merritt, Andrew Kolarich, Michael Kaufmann, William M. Miles, David E. Winchester, Thomas A. Burkart, Matthew McKillop
Format: Article
Language:English
Published: Compuscript Ltd 2021-04-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0005
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author Nikhil H. Shah
Steven J. Ross
Steve A. Noutong Njapo
Justin Merritt
Andrew Kolarich
Michael Kaufmann
William M. Miles
David E. Winchester
Thomas A. Burkart
Matthew McKillop
author_facet Nikhil H. Shah
Steven J. Ross
Steve A. Noutong Njapo
Justin Merritt
Andrew Kolarich
Michael Kaufmann
William M. Miles
David E. Winchester
Thomas A. Burkart
Matthew McKillop
author_sort Nikhil H. Shah
collection DOAJ
description <p class="first" id="d17685867e265"> <b>Background:</b> Implantable cardioverter-defibrillators (ICDs) can be life-saving devices, although they are expensive and may cause complications. In 2013, several professional societies published joint appropriate use criteria (AUC) assessing indications for ICD implantation. Data evaluating the clinical application of AUC are limited. Previous registry-based studies estimated that 22.5% of primary prevention ICD implantations were “non-evidence-based” implantations. On the basis of AUC, we aimed to determine the prevalence of “rarely appropriate” ICD implantation at our institution for comparison with previous estimates. </p><p id="d17685867e270"> <b>Methods:</b> We reviewed 286 patients who underwent ICD implantation between 2013 and 2016. Appropriateness of each ICD implantation was assessed by independent review and rated on the basis of AUC. </p><p id="d17685867e275"> <b>Results:</b> Of 286 ICD implantations, two independent reviewers found that 89.5% and 89.2%, respectively, were appropriate, 5.6% and 7.3% may be appropriate, and 1.8% and 2.1% were rarely appropriate. No AUC indication was found for 3.5% and 3.4% of ICD implantations, respectively. Secondary prevention ICD implantations were more likely rarely appropriate (2.6% vs. 1.2% and 3.6% vs. 1.1%) or unrated (6.0% vs. 1.2% and 2.7% vs. 0.6%). The reviewers found 3.5% and 3.4% of ICD implantations, respectively, were non-evidence-based implantations. The difference in rates between reviewers was not statistically significant. </p><p id="d17685867e280"> <b>Conclusion:</b> Compared with prior reports, our prevalence of rarely appropriate ICD implantation was very low. The high appropriate use rate could be explained by the fact that AUC are based on current clinical practice. The AUC could benefit from additional secondary prevention indications. Most importantly, clinical judgement and individualized care should determine which patients receive ICDs irrespective of guidelines or criteria. </p>
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spelling doaj.art-4a6c4d0383e3449482dfdc8597ff55eb2023-06-28T14:11:22ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822021-04-015423510.15212/CVIA.2021.0005Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective ReviewNikhil H. ShahSteven J. RossSteve A. Noutong NjapoJustin MerrittAndrew KolarichMichael KaufmannWilliam M. MilesDavid E. WinchesterThomas A. BurkartMatthew McKillop<p class="first" id="d17685867e265"> <b>Background:</b> Implantable cardioverter-defibrillators (ICDs) can be life-saving devices, although they are expensive and may cause complications. In 2013, several professional societies published joint appropriate use criteria (AUC) assessing indications for ICD implantation. Data evaluating the clinical application of AUC are limited. Previous registry-based studies estimated that 22.5% of primary prevention ICD implantations were “non-evidence-based” implantations. On the basis of AUC, we aimed to determine the prevalence of “rarely appropriate” ICD implantation at our institution for comparison with previous estimates. </p><p id="d17685867e270"> <b>Methods:</b> We reviewed 286 patients who underwent ICD implantation between 2013 and 2016. Appropriateness of each ICD implantation was assessed by independent review and rated on the basis of AUC. </p><p id="d17685867e275"> <b>Results:</b> Of 286 ICD implantations, two independent reviewers found that 89.5% and 89.2%, respectively, were appropriate, 5.6% and 7.3% may be appropriate, and 1.8% and 2.1% were rarely appropriate. No AUC indication was found for 3.5% and 3.4% of ICD implantations, respectively. Secondary prevention ICD implantations were more likely rarely appropriate (2.6% vs. 1.2% and 3.6% vs. 1.1%) or unrated (6.0% vs. 1.2% and 2.7% vs. 0.6%). The reviewers found 3.5% and 3.4% of ICD implantations, respectively, were non-evidence-based implantations. The difference in rates between reviewers was not statistically significant. </p><p id="d17685867e280"> <b>Conclusion:</b> Compared with prior reports, our prevalence of rarely appropriate ICD implantation was very low. The high appropriate use rate could be explained by the fact that AUC are based on current clinical practice. The AUC could benefit from additional secondary prevention indications. Most importantly, clinical judgement and individualized care should determine which patients receive ICDs irrespective of guidelines or criteria. </p>https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0005
spellingShingle Nikhil H. Shah
Steven J. Ross
Steve A. Noutong Njapo
Justin Merritt
Andrew Kolarich
Michael Kaufmann
William M. Miles
David E. Winchester
Thomas A. Burkart
Matthew McKillop
Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
Cardiovascular Innovations and Applications
title Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
title_full Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
title_fullStr Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
title_full_unstemmed Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
title_short Better Than You Think—Appropriate Use of Implantable Cardioverter-Defibrillators at a Single Academic Center: A Retrospective Review
title_sort better than you think appropriate use of implantable cardioverter defibrillators at a single academic center a retrospective review
url https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0005
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