Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved]
Previous research has demonstrated significant associations between increased levels of ovarian hormones and increased rates of binge eating (BE) in women. However, whereas all women experience fluctuations in ovarian hormones across the menstrual cycle, not all women binge eat in response to these...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-02-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-222/v1 |
| _version_ | 1818509614557167616 |
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| author | Natasha Fowler Phuong T. Vo Cheryl L. Sisk Kelly L. Klump |
| author_facet | Natasha Fowler Phuong T. Vo Cheryl L. Sisk Kelly L. Klump |
| author_sort | Natasha Fowler |
| collection | DOAJ |
| description | Previous research has demonstrated significant associations between increased levels of ovarian hormones and increased rates of binge eating (BE) in women. However, whereas all women experience fluctuations in ovarian hormones across the menstrual cycle, not all women binge eat in response to these fluctuations, suggesting that other factors must contribute. Stress is one potential contributing factor. Specifically, it may be that hormone-BE associations are stronger in women who experience high levels of stress, particularly as stress has been shown to be a precipitant to BE episodes in women. To date, no studies have directly examined stress as a moderator of hormone-BE associations, but indirect data (that is, associations between BE and stress and between ovarian hormones and stress) could provide initial clues about moderating effects. Given the above, the purpose of this narrative review was to evaluate these indirect data and their promise for understanding the role of stress in hormone-BE associations. Studies examining associations between all three phenotypes (that is, ovarian hormones, stress, and BE) in animals and humans were reviewed to provide the most thorough and up-to-date review of the literature on the potential moderating effects of stress on ovarian hormone–BE associations. Overall, current evidence suggests that associations between hormones and BE may be stronger in women with high stress levels, possibly via altered hypothalamic–pituitary–adrenal axis response to stress and increased sensitivity to and altered effects of ovarian hormones during stress. Additional studies are necessary to directly examine stress as a moderator of ovarian hormone–BE associations and identify the mechanisms underlying these effects. |
| first_indexed | 2024-12-10T22:47:50Z |
| format | Article |
| id | doaj.art-4a6de6a1f0184b1b8cb021a532e6f667 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-10T22:47:50Z |
| publishDate | 2019-02-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-4a6de6a1f0184b1b8cb021a532e6f6672022-12-22T01:30:32ZengF1000 Research LtdF1000Research2046-14022019-02-01810.12688/f1000research.16895.118472Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved]Natasha Fowler0Phuong T. Vo1Cheryl L. Sisk2Kelly L. Klump3Department of Psychology, Michigan State University, 316 Physics Road, East Lansing, MI, 48824-1116, USADepartment of Psychology, Michigan State University, 316 Physics Road, East Lansing, MI, 48824-1116, USANeuroscience Program, Michigan State University, 293 Farm Lane, East Lansing, MI, 48824-1116, USADepartment of Psychology, Michigan State University, 316 Physics Road, East Lansing, MI, 48824-1116, USAPrevious research has demonstrated significant associations between increased levels of ovarian hormones and increased rates of binge eating (BE) in women. However, whereas all women experience fluctuations in ovarian hormones across the menstrual cycle, not all women binge eat in response to these fluctuations, suggesting that other factors must contribute. Stress is one potential contributing factor. Specifically, it may be that hormone-BE associations are stronger in women who experience high levels of stress, particularly as stress has been shown to be a precipitant to BE episodes in women. To date, no studies have directly examined stress as a moderator of hormone-BE associations, but indirect data (that is, associations between BE and stress and between ovarian hormones and stress) could provide initial clues about moderating effects. Given the above, the purpose of this narrative review was to evaluate these indirect data and their promise for understanding the role of stress in hormone-BE associations. Studies examining associations between all three phenotypes (that is, ovarian hormones, stress, and BE) in animals and humans were reviewed to provide the most thorough and up-to-date review of the literature on the potential moderating effects of stress on ovarian hormone–BE associations. Overall, current evidence suggests that associations between hormones and BE may be stronger in women with high stress levels, possibly via altered hypothalamic–pituitary–adrenal axis response to stress and increased sensitivity to and altered effects of ovarian hormones during stress. Additional studies are necessary to directly examine stress as a moderator of ovarian hormone–BE associations and identify the mechanisms underlying these effects.https://f1000research.com/articles/8-222/v1 |
| spellingShingle | Natasha Fowler Phuong T. Vo Cheryl L. Sisk Kelly L. Klump Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] F1000Research |
| title | Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] |
| title_full | Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] |
| title_fullStr | Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] |
| title_full_unstemmed | Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] |
| title_short | Stress as a potential moderator of ovarian hormone influences on binge eating in women [version 1; referees: 2 approved] |
| title_sort | stress as a potential moderator of ovarian hormone influences on binge eating in women version 1 referees 2 approved |
| url | https://f1000research.com/articles/8-222/v1 |
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