Clinical proteomics and OMICS clues useful in translational medicine research

<p>Abstract</p> <p>Since the advent of the new proteomics era more than a decade ago, large-scale studies of protein profiling have been used to identify distinctive molecular signatures in a wide array of biological systems, spanning areas of basic biological research, clinical di...

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Main Authors: López Elena, Madero Luis, López-Pascual Juan, Latterich Martin
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Proteome Science
Online Access:http://www.proteomesci.com/content/10/1/35
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author López Elena
Madero Luis
López-Pascual Juan
Latterich Martin
author_facet López Elena
Madero Luis
López-Pascual Juan
Latterich Martin
author_sort López Elena
collection DOAJ
description <p>Abstract</p> <p>Since the advent of the new proteomics era more than a decade ago, large-scale studies of protein profiling have been used to identify distinctive molecular signatures in a wide array of biological systems, spanning areas of basic biological research, clinical diagnostics, and biomarker discovery directed toward therapeutic applications. Recent advances in protein separation and identification techniques have significantly improved proteomic approaches, leading to enhancement of the depth and breadth of proteome coverage.</p> <p>Proteomic signatures, specific for multiple diseases, including cancer and pre-invasive lesions, are emerging. This article combines, in a simple manner, relevant proteomic and OMICS clues used in the discovery and development of diagnostic and prognostic biomarkers that are applicable to all clinical fields, thus helping to improve applications of clinical proteomic strategies for translational medicine research.</p>
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spelling doaj.art-4a6febd6c6f04150bafd23f75347c5ff2022-12-21T21:20:08ZengBMCProteome Science1477-59562012-05-011013510.1186/1477-5956-10-35Clinical proteomics and OMICS clues useful in translational medicine researchLópez ElenaMadero LuisLópez-Pascual JuanLatterich Martin<p>Abstract</p> <p>Since the advent of the new proteomics era more than a decade ago, large-scale studies of protein profiling have been used to identify distinctive molecular signatures in a wide array of biological systems, spanning areas of basic biological research, clinical diagnostics, and biomarker discovery directed toward therapeutic applications. Recent advances in protein separation and identification techniques have significantly improved proteomic approaches, leading to enhancement of the depth and breadth of proteome coverage.</p> <p>Proteomic signatures, specific for multiple diseases, including cancer and pre-invasive lesions, are emerging. This article combines, in a simple manner, relevant proteomic and OMICS clues used in the discovery and development of diagnostic and prognostic biomarkers that are applicable to all clinical fields, thus helping to improve applications of clinical proteomic strategies for translational medicine research.</p>http://www.proteomesci.com/content/10/1/35
spellingShingle López Elena
Madero Luis
López-Pascual Juan
Latterich Martin
Clinical proteomics and OMICS clues useful in translational medicine research
Proteome Science
title Clinical proteomics and OMICS clues useful in translational medicine research
title_full Clinical proteomics and OMICS clues useful in translational medicine research
title_fullStr Clinical proteomics and OMICS clues useful in translational medicine research
title_full_unstemmed Clinical proteomics and OMICS clues useful in translational medicine research
title_short Clinical proteomics and OMICS clues useful in translational medicine research
title_sort clinical proteomics and omics clues useful in translational medicine research
url http://www.proteomesci.com/content/10/1/35
work_keys_str_mv AT lopezelena clinicalproteomicsandomicscluesusefulintranslationalmedicineresearch
AT maderoluis clinicalproteomicsandomicscluesusefulintranslationalmedicineresearch
AT lopezpascualjuan clinicalproteomicsandomicscluesusefulintranslationalmedicineresearch
AT latterichmartin clinicalproteomicsandomicscluesusefulintranslationalmedicineresearch