Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides
The development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available. Polysaccharide-based CSPs are one of the most versatile and widely used for both analytical and preparative applic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-09-01
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| Series: | Symmetry |
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| Online Access: | https://www.mdpi.com/2073-8994/9/9/190 |
| _version_ | 1798026653116399616 |
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| author | João Ribeiro Maria Elizabeth Tiritan Madalena M.M. Pinto Carla Fernandes |
| author_facet | João Ribeiro Maria Elizabeth Tiritan Madalena M.M. Pinto Carla Fernandes |
| author_sort | João Ribeiro |
| collection | DOAJ |
| description | The development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available. Polysaccharide-based CSPs are one of the most versatile and widely used for both analytical and preparative applications and they are able to resolve several classes of racemates. Phenylcarbamates of amylose and cellulose derivatives are the most successful; however, polysaccharide-based CSPs comprising marine-derived polysaccharides are also described revealing high chiral recognition abilities and wider range of mobile phases. A literature survey covering the report on chitin and chitosan based CSPs is presented. The chemical structure of the chiral selectors, their development and applications in chiral LC are emphasized. |
| first_indexed | 2024-04-11T18:38:25Z |
| format | Article |
| id | doaj.art-4a70ecbd37234af7b2f11771e77db856 |
| institution | Directory Open Access Journal |
| issn | 2073-8994 |
| language | English |
| last_indexed | 2024-04-11T18:38:25Z |
| publishDate | 2017-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Symmetry |
| spelling | doaj.art-4a70ecbd37234af7b2f11771e77db8562022-12-22T04:09:04ZengMDPI AGSymmetry2073-89942017-09-019919010.3390/sym9090190sym9090190Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine PolysaccharidesJoão Ribeiro0Maria Elizabeth Tiritan1Madalena M.M. Pinto2Carla Fernandes3Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, PortugalLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, PortugalLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, PortugalLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, PortugalThe development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available. Polysaccharide-based CSPs are one of the most versatile and widely used for both analytical and preparative applications and they are able to resolve several classes of racemates. Phenylcarbamates of amylose and cellulose derivatives are the most successful; however, polysaccharide-based CSPs comprising marine-derived polysaccharides are also described revealing high chiral recognition abilities and wider range of mobile phases. A literature survey covering the report on chitin and chitosan based CSPs is presented. The chemical structure of the chiral selectors, their development and applications in chiral LC are emphasized.https://www.mdpi.com/2073-8994/9/9/190liquid chromatographychiral stationary phasesmarine polysaccharideschitinchitosan |
| spellingShingle | João Ribeiro Maria Elizabeth Tiritan Madalena M.M. Pinto Carla Fernandes Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides Symmetry liquid chromatography chiral stationary phases marine polysaccharides chitin chitosan |
| title | Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides |
| title_full | Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides |
| title_fullStr | Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides |
| title_full_unstemmed | Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides |
| title_short | Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides |
| title_sort | chiral stationary phases for liquid chromatography based on chitin and chitosan derived marine polysaccharides |
| topic | liquid chromatography chiral stationary phases marine polysaccharides chitin chitosan |
| url | https://www.mdpi.com/2073-8994/9/9/190 |
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