Study of concentric, eccentric and split type magnetic membrane micro-mixers

Electromagnetically driven elastic magnetic microfluidic mixers were investigated for their performance in air, water and glycerol filled chambers. They were fabricated by embedding flexible magnets in polydimethylsiloxane (PDMS) membrane. At a driving frequency of 100 Hz, oscillating fluid flow was...

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Main Authors: Shao Qiang Tang, King Ho Holden Li, Ze Ting Yeo, Wei Xuan Chan, Say Hwa Tan, Yong-Jin Yoon, Sum Huan Ng
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Sensing and Bio-Sensing Research
Online Access:http://www.sciencedirect.com/science/article/pii/S221418041730209X
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author Shao Qiang Tang
King Ho Holden Li
Ze Ting Yeo
Wei Xuan Chan
Say Hwa Tan
Yong-Jin Yoon
Sum Huan Ng
author_facet Shao Qiang Tang
King Ho Holden Li
Ze Ting Yeo
Wei Xuan Chan
Say Hwa Tan
Yong-Jin Yoon
Sum Huan Ng
author_sort Shao Qiang Tang
collection DOAJ
description Electromagnetically driven elastic magnetic microfluidic mixers were investigated for their performance in air, water and glycerol filled chambers. They were fabricated by embedding flexible magnets in polydimethylsiloxane (PDMS) membrane. At a driving frequency of 100 Hz, oscillating fluid flow was induced and mixing was achieved. Three designs were fabricated and studied: a) concentric type with the magnetic material in the center of the membrane, b) eccentric type with the magnetic material offset from the center of the membrane and c) split type with two regions of magnetic materials with opposing polarities. The split configuration provides additional fluid folding, facilitating mixing of the 20 μL fluorescent dye in 60 μL of solvent. Simulation and experimental results show that the eccentric and split designs were able to achieve a 20–30% reduction in mixing time compared to the concentric design. At the same magnetic flux density, the eccentric type design exhibited the greatest deflection, explaining the better mixing achieved over the concentric type design. The split type design, having the lowest deflection, was able to perform better and more consistently than the eccentric type design by creating a “micro rocker mixer” effect. We postulated that the shapes of the deflection profiles in the eccentric and split designs contributed to the mixing efficiency by promoting better chaotic advection than the concentric design.
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spelling doaj.art-4a71564c89a345cbb1ff5d500ae5e38c2022-12-22T03:47:25ZengElsevierSensing and Bio-Sensing Research2214-18042018-06-01191423Study of concentric, eccentric and split type magnetic membrane micro-mixersShao Qiang Tang0King Ho Holden Li1Ze Ting Yeo2Wei Xuan Chan3Say Hwa Tan4Yong-Jin Yoon5Sum Huan Ng6School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, SingaporeSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore; Corresponding authors.School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, SingaporeSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, SingaporeQueensland Micro- and Nanotechnology Centre, Nathan Campus, Griffith University, 170 Kessels Road, QLD 4111, AustraliaSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, SingaporeA*STAR's Singapore Institute of Manufacturing Technology (SIMTech), 2 Fusionopolis Way, #08-04, Innovis, 138634, Singapore; Corresponding authors.Electromagnetically driven elastic magnetic microfluidic mixers were investigated for their performance in air, water and glycerol filled chambers. They were fabricated by embedding flexible magnets in polydimethylsiloxane (PDMS) membrane. At a driving frequency of 100 Hz, oscillating fluid flow was induced and mixing was achieved. Three designs were fabricated and studied: a) concentric type with the magnetic material in the center of the membrane, b) eccentric type with the magnetic material offset from the center of the membrane and c) split type with two regions of magnetic materials with opposing polarities. The split configuration provides additional fluid folding, facilitating mixing of the 20 μL fluorescent dye in 60 μL of solvent. Simulation and experimental results show that the eccentric and split designs were able to achieve a 20–30% reduction in mixing time compared to the concentric design. At the same magnetic flux density, the eccentric type design exhibited the greatest deflection, explaining the better mixing achieved over the concentric type design. The split type design, having the lowest deflection, was able to perform better and more consistently than the eccentric type design by creating a “micro rocker mixer” effect. We postulated that the shapes of the deflection profiles in the eccentric and split designs contributed to the mixing efficiency by promoting better chaotic advection than the concentric design.http://www.sciencedirect.com/science/article/pii/S221418041730209X
spellingShingle Shao Qiang Tang
King Ho Holden Li
Ze Ting Yeo
Wei Xuan Chan
Say Hwa Tan
Yong-Jin Yoon
Sum Huan Ng
Study of concentric, eccentric and split type magnetic membrane micro-mixers
Sensing and Bio-Sensing Research
title Study of concentric, eccentric and split type magnetic membrane micro-mixers
title_full Study of concentric, eccentric and split type magnetic membrane micro-mixers
title_fullStr Study of concentric, eccentric and split type magnetic membrane micro-mixers
title_full_unstemmed Study of concentric, eccentric and split type magnetic membrane micro-mixers
title_short Study of concentric, eccentric and split type magnetic membrane micro-mixers
title_sort study of concentric eccentric and split type magnetic membrane micro mixers
url http://www.sciencedirect.com/science/article/pii/S221418041730209X
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