Evaluation of the consistence between the results of immunoinformatics predictions and real-world animal experiments of a new tuberculosis vaccine MP3RT

Evaluation of the consistence between the results of immunoinformatics predictions and real-world animal experiments of a new tuberculosis vaccine MP3RT

BackgroundOur previous study developed a novel peptide-based vaccine, MP3RT, to fight against tuberculosis (TB) infection in a mouse model. However, the consistency between the immunoinformatics predictions and the results of real-world animal experiments on the MP3RT vaccine remains unclear.MethodI...

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Bibliographic Details
Main Authors: Peng Cheng, Yong Xue, Jie Wang, Zaixing Jia, Liang Wang, Wenping Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
tuberculosis (TB)
vaccine
MP3RT
immune responses
computational tools
immunoinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1047306/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1047306/full

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