Axin1 Protects Colon Carcinogenesis by an Immune-Mediated EffectSummary

Axin1 Protects Colon Carcinogenesis by an Immune-Mediated EffectSummary

Background & Aims: Axin1 is a negative regulator of wingless-type MMTV integration site family, member 1 (Wnt)/β-catenin signaling with tumor-suppressor function. The Wnt pathway has a critical role in the intestine, both during homeostasis and cancer, but the role of Axin1 remains elusive....

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Main Authors: Romain Sanson, Silvia Luna Lazzara, David Cune, Caterina Luana Pitasi, Coralie Trentesaux, Marie Fraudeau, Franck Letourneur, Benjamin Saintpierre, Morgane Le Gall, Pascale Bossard, Benoit Terris, Pascal Finetti, François Bertucci, Emilie Mamessier, Béatrice Romagnolo, Christine Perret
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Intestinal Homeostasis
Colon Carcinogenesis
Wnt/β-Catenin Pathway
Axin
Intestinal Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22002314

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