Huang Lian Jie Du Decoction enhances the anti-tumor efficacy of immune checkpoint inhibitors by activating TLR7/8 signalling in melanoma

Huang Lian Jie Du Decoction enhances the anti-tumor efficacy of immune checkpoint inhibitors by activating TLR7/8 signalling in melanoma

Abstract Background The clinical application of immune checkpoint inhibitors (ICIs) is limited by their drug resistance, necessitating the development of ICI sensitizers to improve cancer immunotherapy outcomes. Huang Lian Jie Du Decoction (HLJD, Oren-gedoku-to in Japanese, Hwangryunhaedok-tang in K...

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Bibliographic Details
Main Authors: Suqing Liu, Yaohua Zhang, Xiaohua Zhu, Shan He, Xiao Liu, Xiang Lv, Fuguo Zuo, Jinfeng Wu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Huang Lian Jie Du Decoction
Melanoma
Immunotherapy
Immune checkpoint inhibitors
TLR7/8
IFN-Is
Online Access:https://doi.org/10.1186/s12906-024-04444-y

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