Chrysin Inhibits NF-κB-Dependent <i>CCL5</i> Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment

Chrysin Inhibits NF-κB-Dependent <i>CCL5</i> Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment

Chrysin (5,7-dihydroxyflavone) is a natural polyphenolic compound that induces an anti-inflammatory response. In this study, we investigated the molecular mechanism underlying the chrysin-induced suppression of C-C motif chemokine ligand 5 (<i>CCL5</i>) gene expression in atopic dermatit...

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Bibliographic Details
Main Authors: Hyunjin Yeo, Young Han Lee, Dongsoo Koh, Yoongho Lim, Soon Young Shin
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
atopic dermatitis
CCL5
chemokine
chrysin
mast cell
Online Access:https://www.mdpi.com/1422-0067/21/19/7348

Internet

https://www.mdpi.com/1422-0067/21/19/7348

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