The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study
(1) Background: Surgical-oncological treatment methods are continuously put to the test in times of evidence-based medicine—notably, a constant reevaluation remains key, especially for tumor entities with increasing incidence such as vulvar carcinoma. (2) Methods: In order to determine the postopera...
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MDPI AG
2023-09-01
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| Online Access: | https://www.mdpi.com/2075-1729/13/10/1973 |
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| author | Peter Jankowski Sebastian Findeklee Mihai-Teodor Georgescu Romina Marina Sima Meletios P. Nigdelis Erich-Franz Solomayer Gilbert Georg Klamminger Bashar Haj Hamoud |
| author_facet | Peter Jankowski Sebastian Findeklee Mihai-Teodor Georgescu Romina Marina Sima Meletios P. Nigdelis Erich-Franz Solomayer Gilbert Georg Klamminger Bashar Haj Hamoud |
| author_sort | Peter Jankowski |
| collection | DOAJ |
| description | (1) Background: Surgical-oncological treatment methods are continuously put to the test in times of evidence-based medicine—notably, a constant reevaluation remains key, especially for tumor entities with increasing incidence such as vulvar carcinoma. (2) Methods: In order to determine the postoperative clinical course of different methods of vulvar excision (vulvectomy, hemivulvectomy) as well as inguinal lymph node removal (lymphadenectomy, sentinel lymph node biopsy) with regard to postoperative wound-healingprocess, perioperative hemorrhage, and re-resection rates, we retrospectively analyzed surgical, morphological and laboratory data of 76 patients with a pathological diagnosed vulvar cancer. (3) Results: Analysis of our data from a single center revealed a comparable perioperative clinical course regardless of the chosen method of vulvar excision and inguinal lymph node removal. (4) Conclusions: Thus, our results emphasize the current multimodality in surgical therapy of vulvar carcinoma, in which consideration of known prognostic factors together with the individual patient’s clinical situation allow guideline-based therapy aimed at maximizing surgical safety. |
| first_indexed | 2024-03-10T21:06:46Z |
| format | Article |
| id | doaj.art-4a7d55fd6ed744059b1796ac0d8abe47 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T21:06:46Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-4a7d55fd6ed744059b1796ac0d8abe472023-11-19T17:05:37ZengMDPI AGLife2075-17292023-09-011310197310.3390/life13101973The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric StudyPeter Jankowski0Sebastian Findeklee1Mihai-Teodor Georgescu2Romina Marina Sima3Meletios P. Nigdelis4Erich-Franz Solomayer5Gilbert Georg Klamminger6Bashar Haj Hamoud7Department for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, GermanyDepartment for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, GermanyDepartment of Oncology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, GermanyDepartment for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, GermanyDepartment for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, GermanyDepartment for Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, 66421 Homburg, Germany(1) Background: Surgical-oncological treatment methods are continuously put to the test in times of evidence-based medicine—notably, a constant reevaluation remains key, especially for tumor entities with increasing incidence such as vulvar carcinoma. (2) Methods: In order to determine the postoperative clinical course of different methods of vulvar excision (vulvectomy, hemivulvectomy) as well as inguinal lymph node removal (lymphadenectomy, sentinel lymph node biopsy) with regard to postoperative wound-healingprocess, perioperative hemorrhage, and re-resection rates, we retrospectively analyzed surgical, morphological and laboratory data of 76 patients with a pathological diagnosed vulvar cancer. (3) Results: Analysis of our data from a single center revealed a comparable perioperative clinical course regardless of the chosen method of vulvar excision and inguinal lymph node removal. (4) Conclusions: Thus, our results emphasize the current multimodality in surgical therapy of vulvar carcinoma, in which consideration of known prognostic factors together with the individual patient’s clinical situation allow guideline-based therapy aimed at maximizing surgical safety.https://www.mdpi.com/2075-1729/13/10/1973vulvar cancersurgical oncologyvulvectomyhemi-vulvectomyhemivulvectomylymphadenectomy |
| spellingShingle | Peter Jankowski Sebastian Findeklee Mihai-Teodor Georgescu Romina Marina Sima Meletios P. Nigdelis Erich-Franz Solomayer Gilbert Georg Klamminger Bashar Haj Hamoud The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study Life vulvar cancer surgical oncology vulvectomy hemi-vulvectomy hemivulvectomy lymphadenectomy |
| title | The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study |
| title_full | The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study |
| title_fullStr | The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study |
| title_full_unstemmed | The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study |
| title_short | The Therapy of Vulvar Carcinoma—Evaluation of Surgical Options in a Retrospective Monocentric Study |
| title_sort | therapy of vulvar carcinoma evaluation of surgical options in a retrospective monocentric study |
| topic | vulvar cancer surgical oncology vulvectomy hemi-vulvectomy hemivulvectomy lymphadenectomy |
| url | https://www.mdpi.com/2075-1729/13/10/1973 |
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