Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I>
Objective of the research has been the evaluation of impact of blood liquid part and its separate protein fractions on the process of Yersinia pestis EV NIIEG adhesion to human erythrocytes in vitro . Bacterial binding with target-cells has been registered using photometric technique. Identified has...
| Glavni autori: | , , |
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| Format: | Članak |
| Jezik: | Russian |
| Izdano: |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2013-12-01
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| Serija: | Проблемы особо опасных инфекций |
| Teme: | |
| Online pristup: | https://journal.microbe.ru/jour/article/view/81 |
| _version_ | 1826922430055055360 |
|---|---|
| author | E. V. Pimenov V. A. Oborin A. G. Ivonin |
| author_facet | E. V. Pimenov V. A. Oborin A. G. Ivonin |
| author_sort | E. V. Pimenov |
| collection | DOAJ |
| description | Objective of the research has been the evaluation of impact of blood liquid part and its separate protein fractions on the process of Yersinia pestis EV NIIEG adhesion to human erythrocytes in vitro . Bacterial binding with target-cells has been registered using photometric technique. Identified has been inhibiting effect of blood native plasma and serum, as well as some groups of serum proteins, (albumins and normal immunoglobulins) on attachment of bacteria to human red blood cells. Based on the obtained results it has been assumed that there are two possible mechanisms of suppression of Yersinia pestis EV NIIEG adhesion to human erythrocytes performed by the liquid components of blood – surface microbial structure blockage and erythrocyte membrane receptor shielding. |
| first_indexed | 2024-03-08T13:43:20Z |
| format | Article |
| id | doaj.art-4a7ea7491fe246289c7c58a6ed9fece0 |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2025-02-17T14:09:45Z |
| publishDate | 2013-12-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-4a7ea7491fe246289c7c58a6ed9fece02024-12-24T12:09:50ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2013-12-0104697210.21055/0370-1069-2013-4-69-7281Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I>E. V. Pimenov0V. A. Oborin1A. G. Ivonin2Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences; Vyatka State Agricultural AcademyVyatka State Humanities UniversityKomi Scientific Center of the Ural Branch of the Russian Academy of Sciences; Vyatka State Agricultural AcademyObjective of the research has been the evaluation of impact of blood liquid part and its separate protein fractions on the process of Yersinia pestis EV NIIEG adhesion to human erythrocytes in vitro . Bacterial binding with target-cells has been registered using photometric technique. Identified has been inhibiting effect of blood native plasma and serum, as well as some groups of serum proteins, (albumins and normal immunoglobulins) on attachment of bacteria to human red blood cells. Based on the obtained results it has been assumed that there are two possible mechanisms of suppression of Yersinia pestis EV NIIEG adhesion to human erythrocytes performed by the liquid components of blood – surface microbial structure blockage and erythrocyte membrane receptor shielding.https://journal.microbe.ru/jour/article/view/81штамм y pestis ev нииэгадгезивная активностьэритроцитыплазма и сыворотка кровиальбуминынормальные иммуноглобулиныyersinia pestis ev niieg strainadhesive activityerythrocytesblood plasma and serumalbumincommon immunoglobulins |
| spellingShingle | E. V. Pimenov V. A. Oborin A. G. Ivonin Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> Проблемы особо опасных инфекций штамм y pestis ev нииэг адгезивная активность эритроциты плазма и сыворотка крови альбумины нормальные иммуноглобулины yersinia pestis ev niieg strain adhesive activity erythrocytes blood plasma and serum albumin common immunoglobulins |
| title | Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> |
| title_full | Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> |
| title_fullStr | Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> |
| title_full_unstemmed | Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> |
| title_short | Impact of the Liquid Part and Some Separate Components of Blood on the Process of Interaction between <I>Yersinia pestis</I> EV NIIEG Bacteria and Human Red Blood Cells <I>in vitro</I> |
| title_sort | impact of the liquid part and some separate components of blood on the process of interaction between i yersinia pestis i ev niieg bacteria and human red blood cells i in vitro i |
| topic | штамм y pestis ev нииэг адгезивная активность эритроциты плазма и сыворотка крови альбумины нормальные иммуноглобулины yersinia pestis ev niieg strain adhesive activity erythrocytes blood plasma and serum albumin common immunoglobulins |
| url | https://journal.microbe.ru/jour/article/view/81 |
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