Simultaneous Methylation-Level Assessment of Hundreds of CpG Sites by Targeted Bisulfite PCR Sequencing (TBPseq)

Simultaneous Methylation-Level Assessment of Hundreds of CpG Sites by Targeted Bisulfite PCR Sequencing (TBPseq)

Methylated-DNA sequencing technologies are producing vast amounts of methylome data from cancer samples, from which cancer-associated differentially methylated CpG sites (cDMCs) are continuously identified and filed. The inclusion of as many cDMCs as possible helps improve the accuracy of cancer dia...

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Bibliographic Details
Main Authors: Kyuheum Jeon, Byungkuk Min, Jung S. Park, Yong-Kook Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
cancer
LIFR
targeted NGS
sequencing
diagnosis
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00097/full

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