Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series
Hand Foot Mouth Disease (HFMD) is one of the most common viral illness that is characterised by fever below 38.3°C, painful oral lesions on the tongue and buccal mucosa and macular, maculopapular or vesicular skin lesions on the soles and palms. Many viruses are implicated in HFMD, such as Coxsackie...
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JCDR Research and Publications Private Limited
2022-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/17220/59668_CE(AD)_F(IS)_PF1(AG_OM)_PN(SHU).pdf |
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| author | MG Ravanagomagan M Senthil Kumar AP Krithika |
| author_facet | MG Ravanagomagan M Senthil Kumar AP Krithika |
| author_sort | MG Ravanagomagan |
| collection | DOAJ |
| description | Hand Foot Mouth Disease (HFMD) is one of the most common viral illness that is characterised by fever below 38.3°C, painful oral lesions on the tongue and buccal mucosa and macular, maculopapular or vesicular skin lesions on the soles and palms. Many viruses are implicated in HFMD, such as Coxsackievirus A5, A6, A7, A9, A10, A16 (most common), B1, B2, B3, B5, Echoviruses E3, E4, E9 and Enterovirus 71. The illness is usually mild and self-limiting. HFMD due to enterovirus 71, is associated with a severe illness complicated by aseptic meningitis, acute flaccid paralysis, pulmonary oedema and heart failure. Onychomadesis is a very rare complication of HFMD, typically occurring third to eight week of onset of illness. This is characterised by the detachment of the nail plate from the proximal nail fold by a full thickness sulcus. It is postulated that viral infection causes inflammation around the nail matrix either due to direct effect or due to the deposition of immune complexes secondary to distal thromboembolism. Here, authors report six children of different age groups, who were affected with onychomadesis during an outbreak of HFMD in the month of February to May 2022 in Chennai, Tamil Nadu, India. All these six children developed onychomadesis following HFMD, after a couple of weeks. Both upper and lower limb nails were involved. Other causes of onychomadesis like chronic illness, nutritional deficiencies, drug ingestion, periungual dermatitis, trauma were ruled out. Children were given supportive care and were followed-up. The changes in nails spontaneously regressed after a couple of weeks. |
| first_indexed | 2024-04-10T20:55:27Z |
| format | Article |
| id | doaj.art-4a7fe641bd8942529caaad956454dfad |
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| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T20:55:27Z |
| publishDate | 2022-12-01 |
| publisher | JCDR Research and Publications Private Limited |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-4a7fe641bd8942529caaad956454dfad2023-01-23T06:10:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-12-011612SR01SR0310.7860/JCDR/2022/59668.17220Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case SeriesMG Ravanagomagan0M Senthil Kumar1AP Krithika2Assistant Professor, Department of Paediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.Associate Professor, Department of Paediatrics, Government Tiruppur Medical College and Hospital, Thiruppur, Tamil Nadu, India.Associate Professor, Department of Paediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.Hand Foot Mouth Disease (HFMD) is one of the most common viral illness that is characterised by fever below 38.3°C, painful oral lesions on the tongue and buccal mucosa and macular, maculopapular or vesicular skin lesions on the soles and palms. Many viruses are implicated in HFMD, such as Coxsackievirus A5, A6, A7, A9, A10, A16 (most common), B1, B2, B3, B5, Echoviruses E3, E4, E9 and Enterovirus 71. The illness is usually mild and self-limiting. HFMD due to enterovirus 71, is associated with a severe illness complicated by aseptic meningitis, acute flaccid paralysis, pulmonary oedema and heart failure. Onychomadesis is a very rare complication of HFMD, typically occurring third to eight week of onset of illness. This is characterised by the detachment of the nail plate from the proximal nail fold by a full thickness sulcus. It is postulated that viral infection causes inflammation around the nail matrix either due to direct effect or due to the deposition of immune complexes secondary to distal thromboembolism. Here, authors report six children of different age groups, who were affected with onychomadesis during an outbreak of HFMD in the month of February to May 2022 in Chennai, Tamil Nadu, India. All these six children developed onychomadesis following HFMD, after a couple of weeks. Both upper and lower limb nails were involved. Other causes of onychomadesis like chronic illness, nutritional deficiencies, drug ingestion, periungual dermatitis, trauma were ruled out. Children were given supportive care and were followed-up. The changes in nails spontaneously regressed after a couple of weeks.https://www.jcdr.net/articles/PDF/17220/59668_CE(AD)_F(IS)_PF1(AG_OM)_PN(SHU).pdfbeau’s linecoxsackievirusenterovirusnail platerash |
| spellingShingle | MG Ravanagomagan M Senthil Kumar AP Krithika Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series Journal of Clinical and Diagnostic Research beau’s line coxsackievirus enterovirus nail plate rash |
| title | Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series |
| title_full | Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series |
| title_fullStr | Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series |
| title_full_unstemmed | Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series |
| title_short | Onychomadesis- A Late Manifestation of Hand, Foot and Mouth Disease: A Case Series |
| title_sort | onychomadesis a late manifestation of hand foot and mouth disease a case series |
| topic | beau’s line coxsackievirus enterovirus nail plate rash |
| url | https://www.jcdr.net/articles/PDF/17220/59668_CE(AD)_F(IS)_PF1(AG_OM)_PN(SHU).pdf |
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