Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon
The lymphatic system is an anatomically complex vascular network that is responsible for interstitial fluid homeostasis, transport of large interstitial particles and cells, immunity, and lipid absorption in the gastrointestinal tract. This network of specially adapted vessels and lymphoid tissue pr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/13/18/4554 |
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| author | Mohamed Elshikh Ahmed W Moawad Usama Salem Sergio P Klimkowski Talaat Hassan Brinda Rao Korivi Corey T Jensen Sanaz Javadi Khaled M Elsayes |
| author_facet | Mohamed Elshikh Ahmed W Moawad Usama Salem Sergio P Klimkowski Talaat Hassan Brinda Rao Korivi Corey T Jensen Sanaz Javadi Khaled M Elsayes |
| author_sort | Mohamed Elshikh |
| collection | DOAJ |
| description | The lymphatic system is an anatomically complex vascular network that is responsible for interstitial fluid homeostasis, transport of large interstitial particles and cells, immunity, and lipid absorption in the gastrointestinal tract. This network of specially adapted vessels and lymphoid tissue provides a major pathway for metastatic spread. Many malignancies produce vascular endothelial factors that induce tumoral and peritumoral lymphangiogenesis, increasing the likelihood for lymphatic spread. Radiologic evaluation for disease staging is the cornerstone of oncologic patient treatment and management. Multiple imaging modalities are available to access both local and distant metastasis. In this manuscript, we review the anatomy, physiology, and imaging of the lymphatic system. |
| first_indexed | 2024-03-10T07:50:12Z |
| format | Article |
| id | doaj.art-4a81a9247ca04835aa0be2e4770789d3 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T07:50:12Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-4a81a9247ca04835aa0be2e4770789d32023-11-22T12:16:59ZengMDPI AGCancers2072-66942021-09-011318455410.3390/cancers13184554Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New HorizonMohamed Elshikh0Ahmed W Moawad1Usama Salem2Sergio P Klimkowski3Talaat Hassan4Brinda Rao Korivi5Corey T Jensen6Sanaz Javadi7Khaled M Elsayes8Department of Diagnostic and Interventional Radiology, The University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Diagnostic and Interventional Radiology, Mercy Catholic Medical Center, Darby, PA 19023, USADepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Plastic Surgery, Kasr Alainy School of Medicine, Cairo University, Cairo 11562, EgyptDepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAThe lymphatic system is an anatomically complex vascular network that is responsible for interstitial fluid homeostasis, transport of large interstitial particles and cells, immunity, and lipid absorption in the gastrointestinal tract. This network of specially adapted vessels and lymphoid tissue provides a major pathway for metastatic spread. Many malignancies produce vascular endothelial factors that induce tumoral and peritumoral lymphangiogenesis, increasing the likelihood for lymphatic spread. Radiologic evaluation for disease staging is the cornerstone of oncologic patient treatment and management. Multiple imaging modalities are available to access both local and distant metastasis. In this manuscript, we review the anatomy, physiology, and imaging of the lymphatic system.https://www.mdpi.com/2072-6694/13/18/4554lymphatic system imaginglymphatic system physiologylymphatic system anatomylymphatic metastasislymphangiographylymphoscintigraphy |
| spellingShingle | Mohamed Elshikh Ahmed W Moawad Usama Salem Sergio P Klimkowski Talaat Hassan Brinda Rao Korivi Corey T Jensen Sanaz Javadi Khaled M Elsayes Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon Cancers lymphatic system imaging lymphatic system physiology lymphatic system anatomy lymphatic metastasis lymphangiography lymphoscintigraphy |
| title | Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon |
| title_full | Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon |
| title_fullStr | Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon |
| title_full_unstemmed | Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon |
| title_short | Oncologic Imaging of the Lymphatic System: Current Perspective with Multi-Modality Imaging and New Horizon |
| title_sort | oncologic imaging of the lymphatic system current perspective with multi modality imaging and new horizon |
| topic | lymphatic system imaging lymphatic system physiology lymphatic system anatomy lymphatic metastasis lymphangiography lymphoscintigraphy |
| url | https://www.mdpi.com/2072-6694/13/18/4554 |
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