Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2023-05-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.2c08304 |
| _version_ | 1797810248425144320 |
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| author | Basem Mansour Yomna A. Salem Khaled M. Attallah O. A. El-kawy Ismail T. Ibrahim Naglaa I. Abdel-Aziz |
| author_facet | Basem Mansour Yomna A. Salem Khaled M. Attallah O. A. El-kawy Ismail T. Ibrahim Naglaa I. Abdel-Aziz |
| author_sort | Basem Mansour |
| collection | DOAJ |
| first_indexed | 2024-03-13T07:05:16Z |
| format | Article |
| id | doaj.art-4a834e72ca0d4fb590b46fd90591133e |
| institution | Directory Open Access Journal |
| issn | 2470-1343 |
| language | English |
| last_indexed | 2024-03-13T07:05:16Z |
| publishDate | 2023-05-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj.art-4a834e72ca0d4fb590b46fd90591133e2023-06-06T11:06:43ZengAmerican Chemical SocietyACS Omega2470-13432023-05-01822193511936610.1021/acsomega.2c08304Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling SimulationBasem Mansour0Yomna A. Salem1Khaled M. Attallah2O. A. El-kawy3Ismail T. Ibrahim4Naglaa I. Abdel-Aziz5Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Dakahlia, EgyptDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University − Kantara Branch, Ismailia, EgyptLabeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, EgyptLabeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, EgyptLabeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, EgyptDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Dakahlia, Egypthttps://doi.org/10.1021/acsomega.2c08304 |
| spellingShingle | Basem Mansour Yomna A. Salem Khaled M. Attallah O. A. El-kawy Ismail T. Ibrahim Naglaa I. Abdel-Aziz Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation ACS Omega |
| title | Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation |
| title_full | Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation |
| title_fullStr | Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation |
| title_full_unstemmed | Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation |
| title_short | Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation |
| title_sort | cyanopyridinone and cyanopyridine based cancer cell pim 1 inhibitors design synthesis radiolabeling biodistribution and molecular modeling simulation |
| url | https://doi.org/10.1021/acsomega.2c08304 |
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