Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay
Abstract Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with refractory gout. In the present study, a sensitive...
Main Authors: | Xiao-Yang Zhou, Ling-Jing Yuan, Zhe Chen, Peng-Fei Tang, Xiang-Yu Li, Guo-Xin Hu, Jian-Ping Cai |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | Chemistry Central Journal |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13065-017-0353-6 |
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