Stabilization of Brain Mast Cells Alleviates LPS-Induced Neuroinflammation by Inhibiting Microglia Activation

Stabilization of Brain Mast Cells Alleviates LPS-Induced Neuroinflammation by Inhibiting Microglia Activation

BackgroundThe functional aspects of mast cell-microglia interactions are important in neuroinflammation. Our previous studies have demonstrated that mast cell degranulation can directly induce microglia activation. However, the role of mast cells in Lipopolysaccharide (LPS)-induced microglia activat...

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Bibliographic Details
Main Authors: Hongquan Dong, Yiming Wang, Xiaojun Zhang, Xiang Zhang, Yanning Qian, Haixia Ding, Shu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mast cells
LPS
microglia activation
neuroinflammation
migtation
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00191/full

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