Study of density and distribution of mast cells in endometrium

Introduction: Mast cells are heterogenous group of immune cells involved in multiple biological events they play vital role in various inflammatory and immunological reactions, linking humoral and cell mediated phases of processes. Aim and Objective: In this study we have tried to compare the densit...

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Main Authors: Renuka M. Patil, Nida Nausheen, Saeed Yendigeri
Format: Article
Language:English
Published: Al Ameen Medical College 2023-04-01
Series:Al Ameen Journal of Medical Sciences
Subjects:
Online Access:http://ajms.alameenmedical.org/ArticlePDFs/7%20AJMS%20V16.N2.2023%20p%20134-139.pdf
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author Renuka M. Patil
Nida Nausheen
Saeed Yendigeri
author_facet Renuka M. Patil
Nida Nausheen
Saeed Yendigeri
author_sort Renuka M. Patil
collection DOAJ
description Introduction: Mast cells are heterogenous group of immune cells involved in multiple biological events they play vital role in various inflammatory and immunological reactions, linking humoral and cell mediated phases of processes. Aim and Objective: In this study we have tried to compare the density and distribution of mast cells in various endometrial lesions. Material and Methods: A prospective study with 101 cases of post hysterectomy were studied. Hysterectomy specimens were cut open from anterior wall, incorporated endometrium and myometrium, fixed in 10% formalin after routine processing, embedded in paraffin, 5 micron thickness section taken and stained with Haematoxillin-Eosin, and toludine blue to visualize mast cells. Results: It showed a significant p value which was < 0.001. Conclusion: Mast cell profile may be an additional diagnostic/prognostic tool in different endometrial lesions.
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spelling doaj.art-4a8d51c79a174276aa321c4c672120392023-04-07T05:57:26ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432023-04-011602134139Study of density and distribution of mast cells in endometriumRenuka M. Patil0Nida Nausheen1Saeed Yendigeri2Department of Pathology, Al Ameen Medical College and Hospital, Athani Road, Vijayapur-586108, Karnataka, IndiaDepartment of Pathology, Al Ameen Medical College and Hospital, Athani Road, Vijayapur-586108, Karnataka, IndiaDepartment of Pathology, Al Ameen Medical College and Hospital, Athani Road, Vijayapur-586108, Karnataka, IndiaIntroduction: Mast cells are heterogenous group of immune cells involved in multiple biological events they play vital role in various inflammatory and immunological reactions, linking humoral and cell mediated phases of processes. Aim and Objective: In this study we have tried to compare the density and distribution of mast cells in various endometrial lesions. Material and Methods: A prospective study with 101 cases of post hysterectomy were studied. Hysterectomy specimens were cut open from anterior wall, incorporated endometrium and myometrium, fixed in 10% formalin after routine processing, embedded in paraffin, 5 micron thickness section taken and stained with Haematoxillin-Eosin, and toludine blue to visualize mast cells. Results: It showed a significant p value which was < 0.001. Conclusion: Mast cell profile may be an additional diagnostic/prognostic tool in different endometrial lesions.http://ajms.alameenmedical.org/ArticlePDFs/7%20AJMS%20V16.N2.2023%20p%20134-139.pdfmast celldensity distributionendometrial layer and lesions
spellingShingle Renuka M. Patil
Nida Nausheen
Saeed Yendigeri
Study of density and distribution of mast cells in endometrium
Al Ameen Journal of Medical Sciences
mast cell
density distribution
endometrial layer and lesions
title Study of density and distribution of mast cells in endometrium
title_full Study of density and distribution of mast cells in endometrium
title_fullStr Study of density and distribution of mast cells in endometrium
title_full_unstemmed Study of density and distribution of mast cells in endometrium
title_short Study of density and distribution of mast cells in endometrium
title_sort study of density and distribution of mast cells in endometrium
topic mast cell
density distribution
endometrial layer and lesions
url http://ajms.alameenmedical.org/ArticlePDFs/7%20AJMS%20V16.N2.2023%20p%20134-139.pdf
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AT nidanausheen studyofdensityanddistributionofmastcellsinendometrium
AT saeedyendigeri studyofdensityanddistributionofmastcellsinendometrium