Suicide rates among patients with first and second primary cancer
Abstract Aims With advancements in cancer treatments, the survival rates of patients with their first primary cancer (FPC) have increased, resulting in a rise in the number of patients with second primary cancer (SPC). However, there has been no assessment on the incidence of suicide among patients...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2023-01-01
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| Series: | Epidemiology and Psychiatric Sciences |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2045796023000690/type/journal_article |
| _version_ | 1797685163602214912 |
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| author | Yanting Jiang Yiqi Wang Xiaofei Cheng Ziyang Zhou Jili Wang Haogang Yu Guorong Yao Zhongjie Lu Xin Chen Senxiang Yan Feng Zhao |
| author_facet | Yanting Jiang Yiqi Wang Xiaofei Cheng Ziyang Zhou Jili Wang Haogang Yu Guorong Yao Zhongjie Lu Xin Chen Senxiang Yan Feng Zhao |
| author_sort | Yanting Jiang |
| collection | DOAJ |
| description | Abstract
Aims
With advancements in cancer treatments, the survival rates of patients with their first primary cancer (FPC) have increased, resulting in a rise in the number of patients with second primary cancer (SPC). However, there has been no assessment on the incidence of suicide among patients with SPC. This study assessed the occurrence of suicide among patients with SPC and compared them with that in patients with FPC.
Methods
This was a retrospective, population-based cohort study that followed patients with FPC and SPC diagnosed from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) 17 registries database between 1 January 2000 and 31 December 2019.
Results
For patients with SPC, an age of 85+ years at diagnosis was associated with a higher incidence of suicide death (HR, 1.727; 95% CI, 1.075–2.774), while the suicide death was not considerably different in the chemotherapy group (P > 0.05). Female genital system cancers (HR, 3.042; 95% CI, 1.819–6.361) accounted for the highest suicide death among patients with SPC. The suicide death distribution of patients with SPC over time indicated that suicide events mainly occurred within 5 to 15 years of diagnosis. Compared with patients with FPC, patients with SPC in general had a lower risk of suicide, but increased year by year.
Conclusion
The risk of suicide was reduced in patients with SPC compared with patients with FPC, but increased year by year. Therefore, oncologists and related health professionals need to provide continuous psychological support to reduce the incidence of suicide. The highest suicide death was found among patients with female genital system cancer.
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| first_indexed | 2024-03-12T00:41:06Z |
| format | Article |
| id | doaj.art-4a8ddb02ec58424fbddb0fd9f0e89988 |
| institution | Directory Open Access Journal |
| issn | 2045-7960 2045-7979 |
| language | English |
| last_indexed | 2024-03-12T00:41:06Z |
| publishDate | 2023-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Epidemiology and Psychiatric Sciences |
| spelling | doaj.art-4a8ddb02ec58424fbddb0fd9f0e899882023-09-15T07:21:03ZengCambridge University PressEpidemiology and Psychiatric Sciences2045-79602045-79792023-01-013210.1017/S2045796023000690Suicide rates among patients with first and second primary cancerYanting Jiang0Yiqi Wang1Xiaofei Cheng2Ziyang Zhou3Jili Wang4Haogang Yu5Guorong Yao6Zhongjie Lu7Xin Chen8Senxiang Yan9Feng Zhao10https://orcid.org/0000-0002-4441-9992Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Graduate School, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Graduate School, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. ChinaDepartment of Colorectal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Graduate School, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. ChinaDepartment of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Cancer Center, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Cancer Center, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Cancer Center, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaInstitute of Pharmaceutical Biotechnology, Faculty of Medicine, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Cancer Center, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaDepartment of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China Cancer Center, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaAbstract Aims With advancements in cancer treatments, the survival rates of patients with their first primary cancer (FPC) have increased, resulting in a rise in the number of patients with second primary cancer (SPC). However, there has been no assessment on the incidence of suicide among patients with SPC. This study assessed the occurrence of suicide among patients with SPC and compared them with that in patients with FPC. Methods This was a retrospective, population-based cohort study that followed patients with FPC and SPC diagnosed from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) 17 registries database between 1 January 2000 and 31 December 2019. Results For patients with SPC, an age of 85+ years at diagnosis was associated with a higher incidence of suicide death (HR, 1.727; 95% CI, 1.075–2.774), while the suicide death was not considerably different in the chemotherapy group (P > 0.05). Female genital system cancers (HR, 3.042; 95% CI, 1.819–6.361) accounted for the highest suicide death among patients with SPC. The suicide death distribution of patients with SPC over time indicated that suicide events mainly occurred within 5 to 15 years of diagnosis. Compared with patients with FPC, patients with SPC in general had a lower risk of suicide, but increased year by year. Conclusion The risk of suicide was reduced in patients with SPC compared with patients with FPC, but increased year by year. Therefore, oncologists and related health professionals need to provide continuous psychological support to reduce the incidence of suicide. The highest suicide death was found among patients with female genital system cancer. https://www.cambridge.org/core/product/identifier/S2045796023000690/type/journal_articlepsychological burdensecond primary cancerSEERsuicide death |
| spellingShingle | Yanting Jiang Yiqi Wang Xiaofei Cheng Ziyang Zhou Jili Wang Haogang Yu Guorong Yao Zhongjie Lu Xin Chen Senxiang Yan Feng Zhao Suicide rates among patients with first and second primary cancer Epidemiology and Psychiatric Sciences psychological burden second primary cancer SEER suicide death |
| title | Suicide rates among patients with first and second primary cancer |
| title_full | Suicide rates among patients with first and second primary cancer |
| title_fullStr | Suicide rates among patients with first and second primary cancer |
| title_full_unstemmed | Suicide rates among patients with first and second primary cancer |
| title_short | Suicide rates among patients with first and second primary cancer |
| title_sort | suicide rates among patients with first and second primary cancer |
| topic | psychological burden second primary cancer SEER suicide death |
| url | https://www.cambridge.org/core/product/identifier/S2045796023000690/type/journal_article |
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