<i>N</i>-3-Methylbutyl-benzisoselenazol-3(2H)-one Exerts Antifungal Activity In Vitro and in a Mouse Model of Vulvovaginal Candidiasis

<i>N</i>-3-Methylbutyl-benzisoselenazol-3(2H)-one Exerts Antifungal Activity In Vitro and in a Mouse Model of Vulvovaginal Candidiasis

In the present work, we evaluated the antifungal activities of two novel ebselen analogs, <i>N</i>-allyl-benzisoselenazol-3(2H)-one (<i>N</i>-allyl-bs) and <i>N</i>-3-methylbutylbenzisoselenazol-3(2H)-one (<i>N</i>-3mb-bs). Colorimetric and turbidity a...

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Bibliographic Details
Main Authors: Xiuyi Liang, Agata J. Pacuła-Miszewska, Richa Vartak, Milankumar Prajapati, Haiyan Zheng, Caifeng Zhao, Ganming Mao, Ketankumar Patel, Natalya U. Fedosova, Jacek Ścianowski, Blase Billack
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Current Issues in Molecular Biology
Subjects:
<i>Candida albicans</i>
vulvovaginal candidiasis
ebselen analog
antifungal activity
Pma1p
Online Access:https://www.mdpi.com/1467-3045/46/3/157

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