Depletion of polyfunctional CD26highCD8+ T cells repertoire in chronic lymphocytic leukemia
Key messages CD26highCD8+ cells as potential adoptive immunotherapy candidate CD26highCD8+ T cells are enriched with MAIT cells Galectin-9 preferentially induces apoptosis in CD26highCD8+ T cells Malignant B cells are a source of Galectin-9
Main Authors: | Najmeh Bozorgmehr, Mark Hnatiuk, Anthea C. Peters, Shokrollah Elahi |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
|
Series: | Experimental Hematology & Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40164-023-00375-5 |
Similar Items
-
Chronic Viral Infection Compromises the Quality of Circulating Mucosal–Associated Invariant T Cells and Follicular T Helper Cells via Expression of Inhibitory Receptors
by: Jaisheela Vimali, et al.
Published: (2024-03-01) -
Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy
by: Chie Sugimoto, et al.
Published: (2022-12-01) -
CD161 Expression on Mucosa-Associated Invariant T Cells is Reduced in HIV-Infected Subjects Undergoing Antiretroviral Therapy Who Do Not Recover CD4+ T Cells
by: Michael L Freeman, et al.
Published: (2017-08-01) -
Circulating CD8+ mucosal‐associated invariant T cells correlate with improved treatment responses and overall survival in anti‐PD‐1‐treated melanoma patients
by: Victoria M Vorwald, et al.
Published: (2022-01-01) -
Editorial: CD1- and MR1-restricted T cells in antimicrobial immunity
by: S.M. Mansour eHaeryfar, et al.
Published: (2015-12-01)