Design and Experimental Evaluation of a Peptide Antagonist against Amyloid β(1–42) Interactions with Calmodulin and Calbindin-D28k

Design and Experimental Evaluation of a Peptide Antagonist against Amyloid β(1–42) Interactions with Calmodulin and Calbindin-D28k

Amyloid β<sub>1–42</sub> (Aβ(1–42)) oligomers have been linked to the pathogenesis of Alzheimer’s disease (AD). Intracellular calcium (Ca<sup>2+</sup>) homeostasis dysregulation with subsequent alterations of neuronal excitability has been proposed to mediate Aβ neurotoxicity...

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Bibliographic Details
Main Authors:	Jairo Salazar, Joana Poejo, Ana M. Mata, Alejandro K. Samhan-Arias, Carlos Gutierrez-Merino
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	Amyloid β calmodulin calbindin-D28k antagonist peptide Alzheimer’s disease fluorescence
Online Access:	https://www.mdpi.com/1422-0067/23/4/2289

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