Metabolic reprogramming by adenosine antagonism and implications in non-small cell lung cancer therapy

Metabolic reprogramming by adenosine antagonism and implications in non-small cell lung cancer therapy

Non-small cell lung cancer (NSCLC) is a heterogeneous disease with genetic and environmental parameters that influence cell metabolism. Because of the complex interplay of environmental factors within the tumor microenvironment (TME) and the profound impact of these factors on the metabolic activiti...

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Bibliographic Details
Main Authors: Shuxiao Guan, Shankar Suman, Joseph M. Amann, Ruohan Wu, David P. Carbone, Jie Wang, Mikhail M. Dikov
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Non-small cell lung cancer
Tumor and immune cells
Gene mutation
A2AR/A2BR antagonist
Tumor microenvironment
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622000513

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http://www.sciencedirect.com/science/article/pii/S1476558622000513

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